A.I. Malakhov1, V.V. Kapravchuk2, A.M. Hammoud3, A.R. Malikova4, A.A. Lomonos5, I.D. Nabatov6

1 LLC PRIMEKEY (Moscow, Russia)

2,3,4,5,6 FSAEI HE “Bauman Moscow State Technical University” (Moscow, Russia)

2,3,5,6 Petrovsky National Research Center of Surgery (Moscow, Russia)

3 hammoud@bmstu.ru

Low-frequency pulsed electromagnetic therapy (PEMF) is used in rehabilitation as a non-invasive means of influencing peripheral blood circulation, yet all commercially produced devices operate with fixed protocols and no feedback on the physiological state of the patient. This limits individualization of the exposure, whose effect is regulatory and bidirectional and depends on the initial vascular tone.

The aim of the study is to evaluate the sensitivity of rheovasographic (RVG) parameters to low-frequency electromagnetic field exposure as a first step toward an adaptive electromagnetic therapy system with bioimpedance feedback.

A pilot study was carried out with two healthy volunteers across four independent sessions. The rheographic index (RI) changed by up to 111% (32% on average) within a single 20-minute session, whereas heart rate changed by no more than 20%. The direction of the RI change differed between sessions, and the dynamics of the exposed and control limbs were comparable, indicating a predominantly systemic rather than local response. Owing to the small sample size, no statistical testing was performed and the estimates should be regarded as preliminary. The results confirm that bioimpedance indices are sufficiently sensitive to capture the haemodynamic response to PEMF within a single session and support their use as a feedback signal in a closed-loop control of exposure parameters.

Malakhov A.I., Kapravchuk V.V., Hammoud A.M., Malikova A.R., Lomonos A.A., Nabatov I.D. Preliminary studies of the body’s response to low-frequency electromagnetic therapy // Biomedical Radioelectronics. 2026. V. 29. № 6. P. 44−48. DOI: https://doi.org/10.18127/j15604136-202606-09

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