A.A. Lomonos1, A.R. Malikova2, A.N. Briko3, M.E. Stepanov4, B.A. Akselrod5
1,2,3 FSAEI HE “Bauman Moscow State Technical University” (Moscow, Russia)
1,3,4,5 Petrovsky National Research Centre of Surgery (Moscow, Russia)
3 briko@bmstu.ru
This study evaluates the applicability of the three-temperature heat-transfer model to a wearable, Peltier-based contact thermometric sensor for noninvasive forehead skin perfusion assessment.
A custom multichannel sensor was tested on a healthy volunteer through five heating–cooling cycles at a 40°C target. Passive cooling transients were highly reproducible (R2 = 0.98–0.999) and normalized curves collapsed onto a universal exponential profile ( = = 165.9 ± 37.9 s; A = 6.16 ± 0.53°C).
The reconstructed perfusion index hᵢ/hₑ ≈ 18 and parameter k > 3000 substantially exceeded reference ranges, attributed to thermal inertia of the contact assembly not captured by the first-order formulation. The relaxation time constant τ and amplitude A are proposed as more stable candidate markers of tissue thermal state, applicable to noninvasive microcirculation monitoring.
Lomonos A.A., Malikova A.R., Briko A.N., Stepanov M.E., Akselrod B.A. Experimental evaluation of a three-temperature thermometric system for transient tissue cooling analysis // Biomedical Radioelectronics. 2026. V. 29. № 6. P. 23−27. DOI: https://doi.org/10.18127/j15604136-202606-05
- Ryazantsev P. et al. Approach to Assessing the Resistivity of Head Tissues Based on Finite Element Modeling. 2025 IEEE Ural-Siberian Conference on Biomedical Engineering, Radioelectronics and Information Technology (USBEREIT). 2025. P. 345–348.
- Sessler D.I. Perioperative Thermoregulation and Heat Balance. The Lancet. 2016. V. 387. № 10038. P. 2655–2664. DOI: 10.1016/S0140-6736(15)00981-2.
- Evaluation of the Applicability of Electrical Impedance Methods to Studies of the Microcirculation in the Forehead Based on Numerical Modeling. Biomedical Engineering. 2025. DOI: 10.1007/s10527-025-10469-5.
- Van Genderen M. Peripheral Perfusion in Relation to Systemic Hemodynamics: And its Importance in Critically Ill Patients. 2015.
- Schey B.M., Williams D.Y., Bucknall T. Skin Temperature and Core-Peripheral Temperature Gradient as Markers of Hemodynamic Status in Critically Ill Patients: A Review. Heart & Lung. 2010. V. 39. № 1. P. 27–40. DOI: 10.1016/j.hrtlng.2009.04.002.
- Lal G. et al. An Updated Review of Methods and Advancements in Microvascular Blood Flow Imaging. Microcirculation. 2016. V. 23. № 5. P. 345–363. DOI: 10.1111/micc.12284.
- Ince C. Monitoring Microcirculation in Critical Illness. Current Opinion in Critical Care. 2016. V. 22. № 3. P. 261–268. DOI: 10.1097/MCC.0000000000000335.
- Kurz A., Sessler D. I., Lenhardt R. Perioperative Normothermia to Reduce the Incidence of Surgical-Wound Infection and Shorten Hospitalization. New England Journal of Medicine. 1996. V. 334. № 19. P. 1209–1215. DOI: 10.1056/NEJM199605093341901.
- Ziganurova D.A., Derevesnicova D.A., Luzhnov P.V. Research of Hemodynamic Parameters Variability During Photoplethysmographic Signals Prolonged Registrations. 2024 6th International Youth Conference on Radio Electronics, Electrical and Power Engineering (REEPE). 2024. P. 1–5.
- Ince C. The Microcirculation Is the Motor of Sepsis. Critical Care. 2005. V. 9. Suppl. 4. P. S13. DOI: 10.1186/cc3753.
- Bräuer M. et al. Measuring Core Body Temperature Using a Non-invasive, Disposable Double-Sensor During Targeted Temperature Management in Post-cardiac Arrest Patients. Frontiers in Medicine. 2021. V. 8. DOI: 10.3389/fmed.2021.666908.
- Stepanov M.E. et al. IR Three-Temperature Methods for Assessing the Effect of Anesthetic Induction on Subcutaneous Blood Flow in Various Areas of the Human Face. Optics and Spectroscopy. 2025. V. 133. № 12. P. 1327–1333.

