А.В. Смирнов - д.х.н., Ярославский государственный педагогический университет им. К.Д. Ушинского. E-mail: sav_work@mail.ru С.В. Байков - к.х.н., Ярославский государственный педагогический университет им. К.Д. Ушинского. E-mail: sv.baykov@pharmoslalvl.ru В.Б. Лысков - к.х.н., Ярославский государственный педагогический университет им. К.Д. Ушинского. E-mail: vb.lyskov@pharmoslalvl.ru. А.А. Шетнев - к.х.н., Ярославский государственный педагогический университет им. К.Д. Ушинского. E-mail: aa.shetnev@pharmoslalvl.ru И.Д. Константинова - к.х.н., Институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН). E-mail: kid1968@yandex.ru М.В. Дорогов - д.х.н., профессор, Ярославский государственный педагогический университет им. К.Д. Ушинского. E-mail: dorogov@pharmoslalvl.ru

С целью создания производства дженериков на территории Российской Федерации проведен сравнительный анализ известных методов получения активной фармацевтической субстанции Кладрибин, используемой для производства противоопухолевых средств. В обзоре представлено описание как химических, так и ферментативных методов.

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