L.T. Volova, M.N. Milyakova, V.V. Rossinskaya, V.V. Boltovskaya, L. N. Kulagina, E.I. Pugachev, L.V. Kurganskaya

In the laboratory of human cells cultures IEMB of Samara State Medical University fibroblast-like cells were extracted and grown from human hyaline cartilage. The identification and phenotyping of the obtained culture was held on the 3rd passage. Currently, a new biological model for space research is proposed and developed. Cells were placed on a medium - demineralized allogenic spongiosis, obtained by «Lioplast»® technology. The produced cell-tissue graft was brought on board of «BION-M» №1, using the scientific equipment «Biokont-B». Spaceflight duration - 30 days. At the same time laboratory experiments were made. The presence of cells was identified by LDG assay. The number of cells initially sent, increased 5 times during the space flight. In the laboratory experiments the cells died after 3 weeks without changing the medium, and with the change of medium, the cells retained their morphological and functional properties.