350 rub
Journal Technologies of Living Systems №7 for 2013 г.
Article in number:
Genes expression variation determing cell homeostasis in Down syndrome patients
Keywords: Down syndrome gene expression gene-supressors protooncogens heat-shocks - genes
Authors:
G.D. Zasukhina, G.M. Shagirova, N.V. Reutova, T.N. Maksimova, V.F. Mihajlov
Abstract:
The cells of Down syndrome (DS) patients can be considered as a model to study predisposition to oncogenesis (leucosis), as the number of latter is 15 times higher versus common population level. The expression of such genes as tumor-supressors; protooncogenes; oxidative stress and heat shock stresses was used as a marker of this pathology development. 31 patients with DS and 40 healthy donors were observed in this study.
Pages: 38-44
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