B.S. Gurevich1, F.L. Vladimirov2, D.A. Gribova3

1–3 Institute for analytical instrumentation of RAS (St. Petersburg, Russia)
1 bgurevich48@gmail.com

The development of modern methods for diagnosing various pathologies, including socially dangerous ones such as cancer, requires the detection of diseases at an early stage of their development. Recently, optical diagnostic methods have become widespread. Analysis shows that it is the method of multispectral processing that provides maximum information about the reflection spectrum from a neoplasm and thus increases the reliability of diagnosis. To confirm this, a series of experiments with experimental animals must be conducted.

The aim of study is to develop and test on experimental animals of a multispectral method for treating malignant or benign neoplasms artificially grafted onto animals, as well as verification of its effectiveness in diagnostics. A scientific study was conducted on multispectral image processing of neoplasms in experimental animals using a specially designed light source with adjustable wavelength. An experimental setup for multispectral processing was described. The results of studies of subimages of neoplasms obtained during processing were presented and discussed.

The use of the method allowed us to identify subtle differences in the spectral components of light reflected from the skin of experimental animals with malignant and benign neoplasms and, for comparison, from the skin of healthy animals. It has been shown that the use of a multispectral method allows for reliable diagnosis of various pathologies.

Gurevich B.S., Vladimirov F.L., Gribova D.A. Application of multispectral processing to images of neoplasms in experimental animals. Biomedicine Radioengineering. 2025. V. 28. № 5. P. 105–108. DOI: https:// doi.org/10.18127/j15604136-202505-21 (In Russian)

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