A.A. Satanenko1, I.A. Kudashov2, A.P. Nikolaev3

1–3 Bauman Moscow State Technical University (Moscow, Russia)
1 arti1286@yandex.ru, 2 KydashovV@mail.ru, 3 apnikolaev@yandex.ru

Breast tumors are the leading oncological pathology in the female population, especially in number of new diagnosed cases and the mortality rate. The most dangerous are malignant adenocarcinomas, which grow significantly fast and create metastases in the surrounding organs and tissues. Early detection is the key factor to increase breast cancer survival rate. Cytological or histological analysis based on puncture biopsy are safe procedures allowing for an accurate diagnosis, pivotal for adequate decision-making, including, when indicated, treatment planning. However, result of the analysis strongly depends on the quality of biopsy material. Insufficient accuracy rates under ultrasound control of the needle tip in area, containing a suspicious tumor, may cause false-negative results. This leads to another verification procedure, additional time spent and unnecessary discomfort of the patient. Electroimpedance method was proposed to increase the accuracy rates of the needle tip guidance in breast.

Optimal geometry determination of the electrode system, providing maximum sensitivity in diagnosis of adenocarcinoma based on measurements of the phase angle.

The conclusions obtained as a result of the work on determining the optimal geometry of the electrode system will be used in the development and manufacture of the experimental prototype for biopsy.

Based on dimensions of the breast adenocarcinoma at first stage, the thicknesses of the conductive and insulating layers, the outer diameter and the bevel tip angle of the coaxial electrode system were defined to achieve maximum sensitivity in probing frequency range from 10 to 40 kHz.

In future, electroimpedance and ultrasound methods can be used together to increase the accuracy rates of needle tip guidance in breast.

Satanenko A.A., Kudashov I.A., Nikolaev A.P. Design of the optimal electrode system for biopsy with maximum sensitivity to breast adenocarcinoma. Biomedicine Radioengineering. 2024. V. 27. № 6. P. 67–76. DOI: https:// doi.org/10.18127/j15604136-202406-06 (In Russian)

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