L.Kh. Bragin, A.G. Goncharova, D.L. Bragin, A.M. Nosovsky

State Scientific Center of the Russian Federation – Institute of Biomedical Problems of the RAS (Moscow, Russia)

Despite the fact that the behavior of the human body when exposed to hypoxia has been sufficiently studied, a number of issues need further study. Identification and classification of the body's typical reactions to specific changes in environmental conditions, primarily related to the performance of activities within the framework of extreme professions, remain the actual problem.

The objective of the study was to identify changes in the state of the main indicators of the cardiovascular system – blood pressure (BP), heart rate (HR) and respiratory rate (RR) – in individuals with different background values of these indicators when exposed to conditions of high-altitude hypoxia.

After the study of 43 healthy male volunteers aged 30–35 (conducted according to the original method of raising the subjects in the pressure chamber to a height of 5000 m) it was found the subjects showed different "patterns" of changes in BP, RR and HR, depending on the background values. BP increased in proportion to its background values. The change in RR had a complex dynamics. And the HR increased to approximately the same values in individuals with different values of background indicators.

The revealed patterns of changes in BP, RR and HR should be taken into account when selecting individuals for activities associated with being in conditions of high-altitude hypoxia. The patterns will also make it possible to optimize the work and rest time of persons already engaged in such activities, depending on the physiological characteristics of their body.

Bragin L.Kh., Goncharova A.G., Bragin D.L., Nosovsky A.M. The difference between the adaptive mechanisms of the human body when climbing to a height of 5000 m in the altitude chamber. Biomedicine Radioengineering. 2021. V. 24. № 1. P. 48–53. DOI: 10.18127/j15604136-202101-07 (In Russian).

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