V.E. Antsiperov – Ph.D. (Phys.-Math.), Associate Professor, Leading Research Scientist,  V.A. Kotelnikov Institute of Radio Engineering and Electronics of RAS

E-mail: antciperov@cplire.ru

G.K. Mansurov – Junior Research Scientist, V.A. Kotelnikov Institute of Radio Engineering and Electronics of RAS

E-mail: gkmansurov@gmail.com

A.S. Bugaev – Academician of RAS, Dr.Sc. (Phys.-Math.), Moscow Institute of Physics and Technology

E-mail: bugaev@cplire.ru

Formulation of the problem. Problem statThe cause of cardiovascular diseases in most cases is progressive atherosclerosis. In this regard, the atherosclerosis detecting in early stages (subclinically) is an extremely important aspect of both the prevention of the possible serious consequences of diseases and their prophylaxis. Accordingly, the problem of developing reliable, easy-to-use and inexpensive equipment for estimating the degree of atherosclerotic development in blood vessels is an urgent task that pending early resolution.

The aim of the work. Substantiation of the possibility of solving the presented problem on the basis of the method of estimating the pulse wave velocity using a new type of sensors, developed by the authors – pneumatic sensors for continuous monitoring of blood pressure; the presentation in this connection of a new, indirect method for estimating the delay of the pulse wave at the points of the artery in relation to the moments of R-peak of a synchronous ECG (time points of contraction of the ventricles of the heart); discussion of the details of the method and its modifications in the form of a simplified single-point method for estimating the propagation velocity of a pulse wave.

Results. The results of estimating the pulse wave propagation velocity obtained in the framework of indirect two-point and simplified single-point methods are in full agreement with the known reference values; they correctly reflect age-related trends and correlations with problem cases (heart attack, arrhythmia); quantitative indicators obtained in real experiments confirming this are given in the relevant sections of the work.

Practical value. After necessary refinement of the methodology in accordance with existing medical requirements, pneumatic sensors for continuous monitoring of blood pressure and based on them method for estimating the pulse wave velocity can be used both in clinical and in subclinical diagnostics to assess the degree of atherosclerosis.

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