V.N. Makarov
Dr.Sc. (Phys.-Math.), Professor, Institute of Cybernetics, Moscow Technology University,
Supervisor of the Company «Technosvet», Moscow

A brief review of the ways of a possible solution of the problem of radiofrequency ablation of tumors with a diameter greater than 3 cm without inserting electrodes into the tumor was made. It is shown that such a mode of thermal heating can be realized using single-row and two-row systems whose electrodes are located in the region of ablastics.

1. Dolgushin B.I., Kosy'rev V.Ju. Radiochastotnaya termoablyacziya opuxolej / Pod red. M.I. Davy'dova. M.: Prakticheskaya mediczina. 2015. 192 s.
2. Chang W, Lee J.M., Lee S.M., et al. No-TouchRadiofrequencyAblation: AComparisonofSwitchingBipolarandSwitchingMonopolar Ablation in Ex Vivo Bovine Liver // Korean J. Radiol. 2017. V. 18(2). P. 279–288l.
3. Zhang B., Moser M., Zhang E. et al. A review of radiofrequency ablation: Large target tissue necrosis and mathematical modelling // Physica Medica. 2016. V. 32. P. 961–971.
4. Makarov V.N. Apparatnoe i e'lektrodnoe obespechenie zarubezhny'x i otechestvenny'x ustanovok dlya radiochastotnoj ablyaczii // XIX nauchn.-texn. konf. «Mediko-texnicheskie texnologii na strazhe zdorov'ya» MEDTEX-2017. Sbornik trudov, M.: NII RL im. N.E'. Baumana. 2017. S. 91–100.
5. Makarov V.N., Maxov M.A, Miroshnik V.I. Primenenie mnogoe'lektrodny'x sistem v radiochastotny'x ustrojstvax dlya ablyaczii tkanej proczessom nagreva // Biomediczinskaya radioe'lektronika. 2017. № 4. S. 55–62.
6. Zhang T.Q., Zhang Y.Y., Gu Y.K. et al. Clinical application of multi-electrode synchronous radiofrequency ablation via switching controller for treating large hepatocellular carcinoma // Zhonghua Yi Xue Za Zhi. 2016. Sep. 20. V. 96(35). P. 2777–2780.
7. Choi T.W., Lee J.M., Lee  D.H. et al. Percutaneous Dual-Switching Monopolar Radiofrequency Ablation Using a Separable Clustered Electrode: A Preliminary Study // Korean J. Radiol. 2017 Sep.-Oct. V. 18(5). P. 799–808.
8. Cartier V., Boursier J., Lebigot J., et al. Radiofrequency ablation of hepatocellular carcinoma: Mono or multipolar? // J. Gastroenterol Hepatol. 2016. Mar. V. 31(3). P. 654–660.
9. Seror O., N’Kontchou G., Van Nhieu J.T., et al. Histopathologic comparison of monopolar versus no-touch multipolar radiofrequency ablation to treat hepatocellular carcinoma within Milan criteria // J Vasc IntervRadiol. 2014. V. 25. P. 599–607.
10. Wu L.W., Chen C.Y., Liu C.J., et al. Multipolar radiofrequency ablation with non-touch techniquefor hepatocellular carcinoma ≤ 3 cm: a preliminary report //Adv. Dig. Med. 2014. P. 1:80–85.
11. Hocquelet A., Aubé C., Rode A., et al. Comparison of no-touch multi-bipolar vs. monopolar radiofrequency ablation for small HCC // J Hepatol. 2017. V. 66. P. 67–74 12. Seror O., N’Kontchou G., Nault J. C., et al. Hepatocellular carcinoma within Milan criteria: no-touch multibipolar radiofrequency ablation fortreatment-long-term results // Radiology. 2016. V. 280. P. 611–621.
12. Makarov V.N., Maxov M.A., Miroshnik V.I. Issledovanie mnogoe'lektrodnoj radiochastotnoj ablyaczii v bipolyarnom rezhime pri temperaturnom upravlenii proczessom nagreva // Biomediczinskaya radioe'lektronika. 2017. № 12. S. 36–45.