I.L. Alborova - Post-graduate Student, Biomedical Engineering Department, Research Section of Scientific and Educational Complex «Basic Sciences», Bauman Moscow State Technical University E-mail: alborova@inbox.ru L.N. Anishchenko - Ph.D. (Eng.), Associate Professor, Senior Research Scientist, Research Section of Scientific and Educational Complex «Basic Sciences», Bauman Moscow State Technical University E-mail: anishchenko@rslab.ru

Breast cancer is one of the most common types of cancer among women. Every 9th female in the USA is under the risk of this highly dangerous disease. Due to this fact, providing methods to assess the early-stage diagnosis and treatment of the breast cancer is of a great interest for researchers in the last decades. As a rule, the routine diagnostic procedure consists of individual examination by doctors and mammography or ultrasound screening. Screening for early detection of breast cancer is conducted by these methods at 12-24 month intervals, which cannot guarantee identification of aggressive tumors. As an early screening method in this article describes in detail the experiment of imaging breast tumors using radar aids. The development of microwave breast cancer detection and treatment techniques has been driven by reports of substantial contrast in the dielectric properties of malignant and normal breast tissues. During the experiment, two different phantoms of breast were used: one without the dielectric inclusions, another with dielectric inclusions mimicking malignancy of the breast tissue. The materials of the phantoms were selected in such a way as to its dielectric properties were same the dielectric properties of biological tissues of the breast (normal and malignant). In addition, the usage of this type of materials is convenient to create different configurations of phantoms, and it allows precise installation of the inclusions. During the experiments a vector network analyzer (Rohde&Schwarz) with a single helical antenna attached was used for measuring of S11 parameters. The antenna was pointed to the phantom behind which radio absorbing material was placed to reduce the clutter. Mechanical scanner controlled by Seeduino was used to move the phantom. We conducted measurements at frequencies from 5.6 to 6.6 GHz, 14 to 15 GHz and from 21 to 22 GHz with a step of 0.2 GHz. It was shown that the applied method allows to detect dielectric inhomogeneities in biological tissues. The results, published in the article, have been obtained in the framework of the implementation of the project part of the Russian Foundation for Basic Research (grant No. 16-37-00276). (in part of experimental setup design), the Russian Science Foundation, project #15-19-30012 (in part of microwave imaging processing) and MiMed Cost Action (in part of breast phantom design).

 

1. Breast Cancer. Estimated Incidence, Mortality and Prevalence Worldwide in 2012. URL: http://globocan.iarc.fr/Pages/fact_ sheets_cancer.aspx (Accessed on 01.05.2016).
2. Breast Cancer Diagnosis. URL: http://www.nationalbreastcan­cer.org/breast-cancer-diagnosis (accessed on 01.05.2016).
3. Infrakrasnaja termografija. URL: http://irtis.ru/ (data obrashhenija 03.05.2016).
4. Mikrovolnovaja radiotermometrija v medicine. URL: http://www.radiometry.ru/radiometry/ (data obrashhenija 03.05.2016).
5. Trokhanova O.V., Okhapkin M.B., Korzhenevskijj A.V., Kornienko V.N., CHerepenin V.A. Diagnosticheskie vozmozhnosti metoda ehlektroimpedansnojj mammografii // Biomedicinskaja radioehlektronika. 2009. № 2. S. 66-77.
6. Lazebnik M., McCartney L., Popovic D., Watkins C.B., Lindstrom M.J., Harter J., Sewall S., Magliocco A., Booske J.H., Okoniewski M., Hagness S.C. A large - scale study of the ultrawideband microwave dielectric properties of normal breast tissue obtained from reduction surgeries // Physics in Medicine and Biology. 2007. V. 52. R. 2637-2656.
7. Souvorov A.E., Bulyshev A.E., Semenov S.Y., Svenson R.H., Tatsis G.P. Two-dimensional computer analysis of a micro­wave flat antenna array for breast cancer tomography // IEEE Transactions on Microwave Theory and Techniques. 2000. V. 48. № 8.  R. 1413-1415.
8. Klemm M., Leendertz J.A., Gibbins D., Craddock I.J., Preece A., Benjamin R. Microwave radar-based dierential breast cancer imaging: imaging in homogeneous breast phantoms and low contrast scenarios // IEEE Trans. Antennas Propag. 2010. V. 57.  № 7. R. 2337-2344.
9. Bourqui J., Sill J.M., Fear E.C. A prototype system for measuring microwave frequency reflections from the breast // Int. J. Biomed. Imag. 2012. 12p.
10. Fhager A., Yinan Y., McKelvey T., Persson M. Stroke diagnostics with a microwave helmet // Proc. of the 7th European Conference on Antennas and Propagation (EuCAP - 13). 2013. R. 845-846.
11. Alborova I.L., Anishchenko L.N. Early breast cancer detection. Proceedings of RGC. 2106 [In press].
12. Anishchenko L.N., Alborova I.L., Chizh M.A., Zhuravlev A.V. Microwave imaging of biological tissue phantom in different frequency ranges // PIERS Proceedings, People\'s Republic of China. 2016. August 7-11 [In Press].