L.N. Anishchenko - Ph.D. (Eng.), Associate Professor, Senior Research Scientist, Research Section of Scientific and Educational Complex «Basic Sciences», Bauman Moscow State Technical University E-mail: anishchenko@rslab.ru A.B. Tataraidze - Post-graduate Student, Biomedical Engineering Department, Bauman Moscow State Technical University E-mail: tataraidze@rslab.ru E.М. Rutskova - Ph.D.(Biol.), Research Scientist, IHNA&NPh RAS ( Moscow) E-mail: erutskova@gmail.com

Standard methods, which are currently used in medical practice for prolonged monitoring of laboratory animal respiration, are mostly contact or even invasive. The main drawback of such methods is the necessity of constraining the animal, which may influence the registered physiological parameters values. In case of invasive implanted sensors a surgery is needed to implant them, which is time and labor consuming task. Of course, there are methods, which do not require contact sensor usage, such as whole body plethysmography, however, they are expensive and suitable only for a specific animal type. The above listed facts make creation of a cheap non-contact bioradar, which will be suitable for a prolonged respiration monitoring of different types of animals, an up-to-date task. Such bioradars may be used in testing of novel methods of sleep breathing disorders treatment, for which rodents are the main biological model. As it is know, verification of any novel method for physiological parameters monitoring should be done prior it can be introduced into the clinical practice. There is no information in the literature of such verification experiments for bioradar usage in monitoring rodents or other laboratory animals respiration. In present paper, the method of bioradiolocation was compared with the standard contact method, which are currently used for respiration monitoring in rodents. The experimental results showed a very good agreement between respiratory rates registered by the bioradar and contact sensor: Spearman's correlation coefficients are 0.97 and 0.95 for a rat and a mouse, respectively.

 

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