M.S. Sergeeva - Ph.D. (Biolog.), Associate Professor, Department of Normal Physiology, SSMU, Head of Laboratory of Applied Neurophysiology Center Breakthrough Research «IT - Medicine» SSMU (Samara). E-mail: marsergr@yandex.ru V.F. Pyatin - Dr.Sc. (Med.), Professor, Head of Department of Normal Physiology SSMU, Head of Department of Neurointerface and Applied Neurophysiology Center Breakthrough Research «IT - Medicine» SSMU (Samara). E-mail: pyatin_vf@list.ru E.S. Korovina - Senior Assistant, Department of Normal Physiology SSMU (Samara). E-mail: korovina_ekateri@mail.ru

Circadian regulator in humans is the maximum of the emission spectrum of visible light in the region of 480 nm, which are present in natural sunlight in the early morning and early evening hours [1, 2]. In this paper we first aim was to study the physiological parameters of the students after the light exposure in the region of maximum sensitivity of photosensitive retinal ganglion cells. The study involved 18 SamSMU student volunteers at the age of 18-20: control (CG, n = 10) and experimental (EG, n = 8) groups. The research was doing in early morning hours (7.00. - 9.00) in January. Natural lighting in the room at eye level of test persons was on the average 135 Lk, and brightness - 400 cd/m2. Psychophysiological tests were carried out twice - at the beginning (I phase of the study) and at the end of the study (II phase of the study). In CG interval between testing (between stages I and II studies) was 30 minutes. EG subjects after phase I study for a further 30 minutes using «Device for the normalization of biorhythms» [3, 4], which is an electronic device in the form of points, the blue LEDs which are equipped with special filters that let in light in the blue part of the visible spectrum (478 ± 8 nm), 200 lux, 240 cd/m2. Аfter using the device for the normalization of biorhythms finding an increase in health at 30,14 ± 6,43 % (p < 0,01), activity 22,62 ± 4,53 % (p < 0,05), and the mood in the 14, 29 ± 1,32 % (p < 0,05). Situational anxiety in students EG thus virtually unchanged in the CG increased by 8,75 ± 1,02 % (p < 0,05). At the II stage of the study we also found group differences in health, mood, situational anxiety (p <0,05). At the II stage of the study the students EG we have found an increase in the coefficient of accuracy up to 0,96 ± 0,06 (p < 0,01) when the original value of 0,89 ± 0,09 (Figure). Whereas students CG accuracy factor for stage II studies (0,96 ± 0,05) has not changed relative to the initial state. The parameters of attention and visual perception associated with the volume and speed of information processing at the II stage of the study was significantly increased only in subjects CG. In the course of the stages of research attention span was reduced in subjects of both groups. Thus, the first set acute psychophysiological response in terms of health, activity, mood and accuracy of performance after exposure to light on the retina of the subjects in the field of 478 ± 8 nm in the early morning hours. Further studies will show the importance of preventive applications of artificial light emission in the above blue part of the spectrum for the treatment of desynchronoses.

 

1. Pjatin V.F., Sergeeva M.S., SHirolapov I.V. Morganie kak mekhanizm kontrolja osveshhennosti setchatki i funkcii ee fotochuvstvitelnykh ganglioznykh kletok // Biomedicinskaja radioehlektronika. 2014. № 4. S. 67-68.
2. Patent № 2533965 (RF). Sposob normalizacii cirkadiannykh ritmov cheloveka / V.F. Pjatin, N.P. Romanchuk, P.I. Roman­chuk,V.K. Malyshev, M.S. Sergeeva, A.V. Fadeeva, O.L. Nikitin.
3. Patent №124148 (RF). Ustrojjstvo dlja vozdejjstvija na cirkadiannye chasy cheloveka / V.F.Pjatin.
4. Patent №128494 (RF). Ustrojjstvo dlja vozdejjstvija na bioritmy cheloveka / V.F.Pjatin.