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Journal Biomedical Radioelectronics №4 for 2014 г.
Article in number:
Three-dimensional localization of pathological activity of brain in patients with dyscirculatory encephalopathy
Keywords:
three-dimensional localization
electroencephalogram
dyscirculatory encephalopathy
pathological activity
Authors:
V. P. Omelchenko - Dr.Sc. (Biol.), Professor, Head of the Chair Medical and Biological Physic,
Rostov State Medical University, Russia, Rostov-on-Don. E-mail: vitally.omelchenko@mail.ru
E. A. Kizhevatova - Researcher, Assistant, Chair Medical and Biological Physic, Rostov State Medical University, Russia, Rostov-on-Don. E-mail: alyonatim@mail.ru
E. A. Kizhevatova - Researcher, Assistant, Chair Medical and Biological Physic, Rostov State Medical University, Russia, Rostov-on-Don. E-mail: alyonatim@mail.ru
Abstract:
Recently, the number of people suffering from dyscirculatory encephalopathy to grow. All the more you want to improve the diagnosis of the disease. To date, one of the methods of diagnosis of dyscirculatory encephalopathy is the electroencephalogram (EEG), so it's important to use different methods of analysis to make it more informative.
The purpose of this article is to analyze the three-dimensional localization of the source of the abnormal brain activity in patients with dyscirculatory encephalopathy.
For the identification and localization of pathologic brain bioelectric activity recorded the electroencephalogram on during EEG-Analyzer-21/26 «Encephalan-131-03» firm Medicom MTD. In the program «Encephalan-3D» to search sources use a multistep procedure dipol′s overview of the sources. The essence of localization is to find and calculate the equivalent monodipol the source of the abnormal EEG. Equivalent to the dipole is characterized by the total electrical activity of nerve cells involved in currently in the process of pathological excitation, and is located in the power Center of the hearth. The study involved 30 people with dyscirculatory encephalopathy: 12 women (40%) and 18 men (60%). the age of patients ranged from 52 to 78 years, mean age was 69.1 ± 2.6 (p > 0.95) years. All test subjects filmed EEG in the background: the patient is in a relaxed position with closed eyes. Then have the Visual analysis of EEG and have identified the existence of pathological elements or signature disrupt the normal functioning of the brain. Then take the 2 seconds long EEG recordings, on which there was a pathology. It was determined the total number of dipoles, describing the rejection as well as the number of dipoles in the right and left hemispheres in the Middle, frontal and central structures of the brain stem.
The three-dimensional localization in patients with dyscirculatory encephalopathy indicate the presence of dipole in the depths of the brain stem and midline structures, as well as in the frontal, temporal and occipital areas that confirms the presence of cognitive impairment in patients with dyscirculatory encephalopathy.
Pages: 63-64