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Journal Biomedical Radioelectronics №3 for 2013 г.
Article in number:
Changes of microbiological parameters of the covering tissues surveyed in conditions 520-day isolation
Keywords: confined habitat covering tissues colonial resistence disorders microbiological parameters
Authors:
V.K. Ilyin, Z.O. Solovieva, A.M. Nosovsky, E.V. Kaminskaya
Abstract:
The adverse factors of space flight influencing an organism of the person are weightlessness, gipodinamiya, space radiation and the stress caused by long stay in confined habitat . Researches earlier were carried out in ground conditions on studying influence of the factor of weightlessness and long stay surveyed in confined habitat of limited volume. Practically at all surveyed person, changes of a microbic landscape of the covering tissues of a various sort have been fixed. Experiment «Mars-500» has given a unique opportunity to estimate influence of isolation of 520 days in confined habitat on microflora of the covering tissues at verifiers - volunteers. The purpose of the work was carrying out researches of microbiological parameters of the covering tissues of the volunteers participating in experiment. The researches of a condition microflora of the covering tissues was carried at 6 person. Researches of bacterial microflora of the covering tissues were carried out in to the background period, after 7, 14, 21, 75, 90, 120, 150, 180, 210, 240, 270, 300, 330, 360, 390, 420, 450, 480, 510 days of experiment, and after 7 and 14 days upon termination of the experiment. Specific structure in each group was defined by means of commercial biochemical test-systems (Lachema). Statistical data processing was carried out by the two-factorial dispersive analysis. Dynamics of quantitative characteristics of microflora of the covering tissues for surveyed persons confirms periodic character of accumulation of potential of pathogenicity in the system person-microbe that reflects the general tendency of change of microflora of the person in the confined habitat. Correction of disbiotics changes of a microbic landscape of integumentary fabrics is necessary.
Pages: 53-57
References
  1. Viktorov A.N. Medicinskoe znachenie osobennostejj formirovanija ehkologicheskojj sistemy chelovek - mikroorganizmy v obitaemykh germozamknutykh obektakh // Tezisy dokl. VIIIVsesojuz. konf. po probl. kosmich. biologii i aviakosmich. mediciny. Kaluga. M.: Nauka. 1986. C. 221-222.
  2. Ilin V.K., Volozhin A.I., Vikha G.V. Kolonizacionnaja rezistentnost organizma v izmenjonnykh uslovijakh obitanija. M.: Nauka. 2005. C. 276.
  3. Ilin V.K., Krjukov A.I., Volozhin A.I. i dr. Issledovanie disbioza, razvivajushhegosja v uslovijakh «sukhojj» immersii, i metody ego korrekcii // Aviakosmicheskaja i ehkologicheskaja medicina. 2008. № 5. C. 70-74.
  4. Ilin V.K., Soloveva Z.O., Skedina M.A.EHkspress-diagnostika mikrobnogo statusa cheloveka v uslovijakh 14- i 105-sutochnojj izoljacii // Aviakosmicheskaja i ehkologicheskaja medicina. 2011. № 1. C. 49-52.
  5. Labinskaja A.S. Mikrobiologija s tekhnikojj mikrobiologicheskikh issledovanijj. M.: Medicina. 1978.
  6. Morukov B.V., Rykova M.P., Antropova E.N. i dr. Issledovanie sistemy immuniteta cheloveka v uslovijakh 520-sutochnojj izoljacii v germoobekte // Sb. materialov. Mezhdunar. simpoziuma po rezultatam ehksperimentov, modelirujushhikh pilotiruemyjj polet na Mars (Mars-500). 23-25 aprelja 2012. Moskva. S. 41-42.
  7. Nosovskijj A.M., Soloveva Z.O., Ilin V.K. Primenenie metoda glavnykh komponent dlja ocenki odnorodnosti rezultatov issledovanijj mikroflory v uslovijakh «sukhojj» immersii // Biomedicinskaja radioehlektronika. 2012. № 2. S. 42-47.
  8. Polikarpov N.A., Viktorov A.N., KHalangot A.F. Nukleaznaja aktivnost mikroorganizmov i problema kontrolja za sostojaniem automikroflory operatorov germetichno - zamknutykh obektov // Kosmicheskaja biologija i aviakosmicheskaja medicina. 1991. № 6. C. 39-42.
  9. Prikaz MZ № 535 «Ob unifikacii mikrobiologicheskikh (bakteriologicheskikh) metodov issledovanija, primenjaemykh v kliniko-diagnosticheskikh laboratorijakh lechebno-profilakticheskikh uchrezhdenijj» ot 22.04.1985 g.
  10. Soloveva Z.O., Ilin V.K., Nosovskijj A.M., Batov A.B., Savina N.V. Izmenenie mikrobiologicheskikh pokazatelejj slizistykh obolochek verkhnikh dykhatelnykh putejj obsleduemykh v uslovijakh «sukhojj» immersii // Tekhnologija zhivykh sistem. 2011. T. 8. № 3. S. 61-64.
  11. SHeffe G. Dispersionnyjj analiz: per. s angl. M. 1963. S. 626.