Y.E. Kirpichenko, D.P. Timohin, S.I. Shchukin, I.A. Kudasho, A.N. Tihomirov

Development of biotechnological systems capable for a long-time perform automatic monitoring of hemodynamic parameters, respectively in a timely manner to help the physician controlling pathological changes in the functional state of the cardiovascular system is an urgent task. One such technology is the vector rheocardiography method, whose peculiarity is the electrode system corresponds to individual anatomical features of the heart geometry and location. For research a multichannel hardware-software complex has being used, it allows measuring impedance by using tetrapolar technique with up to 30 precardiac channels. Developed software allows calculating stroke volume and ejection fraction by impedance measurements processing in real-time for each cardiac cycle. The results of preclinical studies of the developed technique found the accuracy of vector rheocardiography technology is congruent to the accuracy of magnetic resonance imaging and ultrasound studies.