A.A. Tsymbal

It is known that H. Selye described a number of endocrine, cardiovascular, nervous, digestive and reproductive changes caused by stress factors that threaten homeostasis. The most notable of neu-roendocrine markers of stress - it's fast rise levels of corticotropin-releasing factor, corticotropin and glucocorticoids, activation of the hypothalamic noradrenergic impulses, increases the formation of glucose in the liver and the elevated release of hyperglycemic hormones: epinephrine and glucagon, while there is also a drop in insulin levels, which mediates is epinephrine. From the above mentioned endocrine changes comes metabolic response that includes, above all, a persistent increase in plasma glucose levels, increased consumption of oxygen by cells and tissues, glycolysis, glycogenolysis and gluconeogenesis, the splitting of the protein, altering the activity of blood enzymes. Analysis of literature data concerning the protein-synthetic function of the liver, the nature of the shifts of the protein spectrum of blood in different types of experimental stress indicates their ambiguous and contradictory. It is known that one of the factors stress damage to organs and tissues is the dominance of the decay processes of proteins over the rate of resynthesis due to change in the balance «anabolic» and «catabolic» hormones. The purpose of this study was to explore the nature of the effects of electromagnetic terahertz waves at frequencies of molecular spectrum of emission and absorption of nitric oxide 150,176-150,664 GHz on the changed parameters of metabolic status in rats - males during acute stress. Studied blood samples from 60 white mongrel male rats weighing 180-220 g. As the model simulating disturbances of metabolic status in white male rats, acute immobilization stress applied - fixed rats on their backs for 3 hours once. Irradiation of animals was carried out by electromagnetic waves at frequencies of molecular spectrum of emission and absorption of nitric oxide 150,176-150,664 GHz using the apparatus of "UHF-NO», on skin with an area of 3 cm above the xiphoid process of sternum area. Irradiator at a distance of 1.5 cm above the animal's body. Radiation power of a device-0 7mVt, and power density incident on the skin area of 3 cm was 0.2 mW/cm2. When analyzing the results of the study showed that rats kept in a state of acute immobilization stress, we observed statistically significant compared with a group of intact animals, changes in metabolic status, as reflected primarily an increase in the concentration of glucose in blood plasma. It was found that the total amount of protein in the blood serum of male rats subjected to experimental acute immobilization stress, decreased as compared with the intact animals. This changes the qualitative structure of the protein spectrum of blood: the level of albumin in the blood significantly decreased, while the percentage of protein globulin fraction were significantly increased. On the background of an acute immobilization stress application of electromagnetic terahertz waves at frequencies of nitric oxide 150,176-150,664 GHz in experimental animals for 5 minutes does not lead to normalization of the changed parameters of metabolic status. Irradiation stressirovannyh animals terahertz electromagnetic waves at frequencies of nitric oxide 150,176-150,664 GHz for 15 minutes leads to only partial recovery of the changed parameters of metabolic status. Application of electromagnetic terahertz waves at frequencies of molecular spectrum of nitrogen oxide 150,176-150,664 GHz for 30 minutes causes complete normalization poststressornyh changes of metabolic status in experimental animals. Fully normalized modified carbohydrate metabolism, protein spectrum of blood, the concentration of molecules of average mass activity of the major enzymes, and their values are not statistically significantly different from those of the control group.