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Journal Biomedical Radioelectronics №2 for 2009 г.
Article in number:
The Influence of Coherent Electromagnetic Waves of Millimeter Range on the Properties of the DNA Solutions
Authors:
Babayan Yu. S., Tadevosyan A.A., Kanaryan G. L., Kalantaryan V. P., Babayan S.Yu., Vardevanyan P. H
Abstract:
At present, millimetric electromagnetic (MEM) waves of low intensity are successfully used in clinical medicine in spite of the fact that mechanism of their action on biological objects is yet not clarified. It is assumed that primary target of reception of MEM waves in a biological system are the molecular structures of water molecules. With densitometrical and spectrometrical methods density and thermostability of DNA water-salt solutions irradiated with nonthermal MEM waves resonant for water structures of frequencies 64.5 GHz and 50.3 GHz and nonresonant frequency 48.3 GHz were investigated. Experiments have shown that with the increase of time of irradiation with resonant frequencies from 0 (not irradiated) to 120 min. thermostability of the DNA and density of its solutions were increasing approximately by 1оC and 10-4 G/sm3 accordingly. If irradiated by nonresonant frequency of 48.3 GHz, the increase in thermostability of DNA and densities of its solutions are in the margin of the experimental error. It is expected that under the action of low intensity MEM radiation of millimeter range dehydration of DNA and Na+ ions present in solution takes place.  Knowing values of density ρ ('Г) in temperature interval 2080о С for not irradiated as well as irradiated (64.5 and 50.3 GHz frequencies) DNA solutions coefficient of thermal expansion is possible to calculate by formula α=(?d ln ρ )/ dT.  Calculations show that with increase of temperature an increase in α for investigated solutions is observed.  In temperature interval 2050оС, irradiation of solutions with resonant frequencies for water structures, values of α are almost not influenced. At temperatures above 50оС, coefficient α is lower for irradiated samples in comparison with corresponding not irradiated ones. The obtained experimental data are possible to explain if we assume that irradiation and increase in the temperature obstructs the possibility of forming of linear hydrogen bonds.
Pages: 52
References
  1. Makar V.R., Logani M.K., Bhanushali A. et al. - Bioelectromagnetics, 2005, vol. 26, no. 1, p. 10.
  2. Belyaev I.Y., Shcheglov V.S., Alipov Y.D., Polunin V.A. - Bioelectromagnetics, 1996, vol. 17, no. 4,  pp. 312 - 321.
  3. Девятков Н.Д., Голант М.Б., Бецкий О.В. Миллиметровые волны и их роль в процессах жизнедеятельности. - М.: Радио и связь, 1991, с. 169.
  4. Петросян В.И., Синицын Н.И., Елкин В.А. и др. - Биомедицинская радиоэлектроника, 2001, № 5 - 6,  с. 62 - 105.
  5. Fesenko E.E., Gluvstejn A.Ya. - FEBS Letters, 1995, vol. 367, pp. 53 - 55.
  6. Tikhoirova A. Chalikian T.V. - J. Mol. Biol., 2004, vol. 341, pp. 551 - 563.
  7. Markarian S.A., Asatryan A.M., Grigoryan K.R., Sargsyan H.R. - Biopolymers, 2006, vol. 81, pp. 1 - 5.
  8. Сафронова В.Г., Гапеев А.Б., Аловская А.А. и др. - Биофизика, 1997, т. 42, № 6, с. 1267 - 1273.
  9. Бабаян Ю.С., Акопян С.Н., Казарян Р.С. и др. - Биомедицинские технологии и радиоэлектроника, 2006, № 11, с. 64 - 68.
  10. Бабаян Ю.С., Маркарян А.Ш., Калантарян В.П. и др. - Биофизика, 2007, т. 52, № 2, с. 382 - 384.
  11. Петросян В.И., Майбородин А.В., Дубовицкий С.А. и др. - Миллиметровые волны в биологии и медицине, 2005, № 1, с. 18 - 31.
  12. Илларионов В.Е. Медицинские информационно-волновые технологии. - М.: ВЦМК «Защита», 1998.
  13. Высоцкий В.И., Корнилова А.А. ? Вестник Московского университета. Сер.3. Физика. Астрономия, 2004, № 3,  с. 58 - 62
  14. Егоров Г.И., Сырбу А. А., Колкер А.А. ? Журнал общей химии, 2002, т. 72, № 5, с. 744 - 746.