350 rub
Journal №5 for 2011 г.
Article in number:
Zinc Deficiency in Humans: Major Clinical Effects and Diagnostic Criteria
Authors:
A.S. Prasad
Abstract:
Deficiency of zinc is prevalent in human populations throughout the world. Major clinical effects of zinc deficiency in humans include growth retardation, immune system disorders and cognitive impairment. The ability of zinc to function as an antioxidant and stabilize membranes suggests that it has a role in prevention of free radical induced injury during inflammatory processes. Zinc deficiency can be diagnosed by measurement of zinc level in blood plasma, red cells, hair or urine. Zinc determination in granulocytes and lymphocytes, however, reflect the body zinc status more accurately. Quantitative assay of alkaline phosphatase activity in granulocytes, thymulin activity in plasma and IL-2 expression in mononuclear cells are also suggestive useful tools for zinc deficiency evaluation.
Pages: 29-36
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