Adjuvants, used in technologies suppositories
- 1 aspirant, All-Russian Institute of Medicinal and Aromatic Plants, Moscow, RUSSIA
- 2,3,4 Ph.D., (pharm.) All-Russian Institute of Medicinal and Aromatic Plants, Moscow, Russia
- 5 Dr. Sc. (pharm.), Prof., All-Russian Research Institute of Medicinal and Aromatic Plants, Moscow, Russia
Abstract
Due to a number of advantages suppository, as medicinal form: the introduction way, accuracy of dispensing, bioavailability, their nomenclature constantly increases. Requirements to suppository bases can be divided conditionally on technological and biopharmaceutical. Bases suppository should provide their chemical and physical stability in the course of use, storages and to have ability easy to be formed and keep hardness at introduction. From the biopharmaceutical point of view the basis for suppository should be chemically indifferent and promote liberation of medicinal substances. Quality suppository should correspond to GF XI requirements.
How to cite
Михеева Н.С., Охотникова В.Ф., Джавахян М.А., Качалина Т.В., Сокольская Т.А. Вспомогательные вещества, применяемые в технологии суппозиториев // Вопросы биологической, медицинской и фармацевтической химии. 2013. № 9. С. 16–19.
References
- Gosudarstvennaya farmakopeya SSSR: XI izd., vy'p. 2 M.: Mediczina. S. 151-152.
- Gosudarstvenny'j reestr lekarstvenny'x sredstv. 2011.
- Zamaraeva E.E., Kozlova N.G, Dranik L.I. Nekotory'e osobennosti sozdaniya lekarstvenny'x sredstv v forme suppozitoriev // Farmacziya. 1992. T. 41. № 6. S. 80-83.
- Zotova A.V. Razrabotka sostava, texnologii i standartizaczii suppozitoriev dlya podgotovki shejki matki k rodam: Avtoref. ... diss. k.farm.n. Moskva. 2008 g.
- Zotova A.V., Popkov V.A. Izuchenie texnologii i sostava sovremenny'x suppozitoriev dlya akusherskoj praktiki // Materialy' zaochnoj mezhdunar. konf. «Prioritety' farmaczevticheskoj nauki i praktiki» MMA im. I.M. Sechenova. 2006. S. 198-200.
- Marchenko L.G., Rusak A.V., Smexova I.E. Texnologiya myagkix lekarstvenny'x form (uchebnoe posobie). SPb. 2004.
- http:\\www. Provisor. Com. Ua\ Svechi, ukroshhayushhie pozhar (OAO «Nizhfarm», RF). Provizor. Zhurnal dlya rabotnikov farmaczii i medicziny'. 2004. №21.