Determination of biological activity of essential oil from needles of Pinus Sibirica and its different fractions by the test-system in vitro

N.A. Polyakov; V.A. Dubinskaya; A.A. Efremov; E.A. Efremov

Determination of biological activity of essential oil from needles of Pinus Sibirica and its different fractions by the test-system in vitro

N.A. Polyakov¹, V.A. Dubinskaya², A.A. Efremov³, E.A. Efremov⁴

research article Pages: 4-8

¹ Ph.D. (Biol.), Leading Research Sientist, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (VILAR), Moscow, Russia
² Ph.D. (Biol.), All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (VILAR), Moscow, Russia
³ Dr.Sc. (Chem.), Professor, Siberian Federal University, Krasnoyarsk, Russia
⁴ Student, Siberian Federal University, Krasnoyarsk, Russia

Keywords: Pinus Sibirica essential oil enzymatic test systems in vitro biological activity

Abstract

Forty four component are determined, the main are α-pinene (60,7 %), β-phellandrene (20,9 %), β-pinene (4,5 %), δ-cadinene (1,9 %). Significant differences in the composition of different fractions of essential oil are indentified. Different fractions of essential are tested on the biological activity by enzymatic test systems in vitro. It was found that the biological activity of the essential oil of Pinus Sibirica is highly dependent on the content of its main components, such as α-pinene, β-phellandrene, γ-, δ-cadinene.

How to cite

Поляков Н.А., Дубинская В.А., Ефремов А.А., Ефремов Е.А. Биологическая активность эфирного масла древесной зелени сосны сибирской (Pinus sibirica) и его отдельных фракций с использованием тест-систем in vitro // Вопросы биологической, медицинской и фармацевтической химии. 2013. № 12. С. 4–8.

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[2] Belousova N.I. Sostav e'firny'x masel bagul'nikov flory' Sibiri i rossijskogo Dal'nego Vostoka: Diss. - kand. xim. nauk. Novosibirsk. 1996. 140 s.

[3] Vojtkevich S.A., Xejficz L.A. Ot drevnix blagovonij k sovremenny'm parfyumerii i kosmetike. M. 1997. 215 s.

[4] Kolesnikova R.D., Tagil'czev Ju.G. Osobennosti ximicheskogo sostava i fiziko-ximicheskix xarakteristik xvojny'x e'firny'x masel razny'x stran mira // Lesny'e biologicheskie veshhestva. Xabarovsk. 2001. S. 202-207.

[5] By'kov V.A., Dubinskaya V.A., Rebrov L.B., Mineeva M.F., Skuridin S.G., Evdokimov Ju.M. Kompleksny'j podxod k izucheniyu mexanizmov dejstviya protivomikrobny'x i protivovirusny'x sredstv. Ximiko-farmaczevticheskij zhurnal. T. 42. № 3. 2008. S. 3-8.

[6] Shchipitsyna O.S., Efremov A.A. Composition of ethereal oil isolated from various vegetative parts of angelica from the Siberian Region // Russian Journal of Bioorganic Chemistry. 2011. V. 37. № 7. P. 888-889.

[7] Efremov A.A., Strukova E.G., Narchuganov A.N. Komponentny'j sostav e'firnogo masla lapki xvojny'x Sibirskogo regiona po danny'm xromato-mass-spektrometrii // Zhurnal Sibirskogo federal'nogo universiteta. Ser. Ximiya. 2009. № 4. S. 335-350.

[8] Korolyuk M.A., Ivanova L.I., Majorova I.G., Tokareva V.E. // Laboratornoe delo. 1986. № 1. S. 16-19.

[9] Beutler E. Red cell metabolism. Churchill. Livingson. N-Y. 1986. S. 60 - 69.

[10] Patent № 2181892 (RF)., Sposob vy'yavleniya veshhestv, obladayushhix antioksidantny'mi svojstvami, in vitro / V.A. Dubinskaya, V.A. By'kov, M.F. Mineeva, L.B. Rebrov, V.K. Kolxir.

[11] Granik V.G. Osnovy' mediczinskoj ximii. 2-e izd. M.: Vuzovskaya kniga. 2006. 384 s.

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