The using of the modern equipment for providing of the platelet concentrate safety in institution of blood service

Александр Григорьевич Гудков; Александр Викторович Чечёткин; Михаил Иванович Лазаренко; Виталий Юрьевич Леушин; Александр Фёдорович Бобрихин; Иван Николаевич Маржановский; Александра Сергеевна Борозинец; Вахтанг Нодарович Лемонджава

The using of the modern equipment for providing of the platelet concentrate safety in institution of blood service

Александр Григорьевич Гудков¹, Александр Викторович Чечёткин², Михаил Иванович Лазаренко³, Виталий Юрьевич Леушин⁴, Александр Фёдорович Бобрихин⁵, Иван Николаевич Маржановский⁶, Александра Сергеевна Борозинец⁷, Вахтанг Нодарович Лемонджава⁸

research article Pages: 50-56

¹ д.т.н., профессор, МГТУ им. Н.Э. Баумана
² д.м.н., профессор, директор ФГБУ «Российский научно-исследовательский институт гематологии и трансфузиологии Федерального медико-биологического агентства» (Санкт-Петербург)
³ д.м.н., зав. консультативно-диагностическим центром, ГКБ № 1 им. Н.И. Пирогова Департамента здравоохранения г. Москвы
⁴ к.т.н., зам. генерального директора, ООО «НПИ ФИРМА «ГИПЕРИОН» (Москва)
^5,8 начальник отдела, ООО «НПИ ФИРМА «ГИПЕРИОН» (Москва)
⁶ лаборант, МГТУ им. Н.Э. Баумана
⁷ техник, МГТУ им. Н.Э.Баумана

Keywords: medical equipment blood service platelet concentrate donor

Abstract

This article illustrates the use of modern equipment for storage safety of the platelet containing concentrate. Basic re-quirements of the platelet containing concentrate device safe storage is completed. The high-tech medical care involves the use of modern technology in hematology, oncology, cardio-surgery and other medicine area, but it is impossible without use of safety, biologically full and clinical effective blood component and preparation. The results of research efficiency of using modern equipment of the platelet containing concentrate safety storage in blood service institution is presented. The requirements of the platelet containing transfusion media is completed. Design concept of the platelet containing transfu-sion media safety storage equipment with use the thermal stabilization system based on semiconductor thermoelectric elements and with use information support for monitoring the storage process. The new approach for the construction of the device for thermal treatment and storage of blood components and products providing safety of the platelet concentrate in the blood service institutions is presented. The estimation of efficiency of use the thermoelectric elements to achieve the necessary accuracy of storage temperature for containing platelets transfusion media is presented. The system of registra-tion of all parameters operation of the device for thermal processing and storage of blood components and products to improve the reliability and reduce the possibility of sudden it fails is completed. Analysis devices operating parameters protocol reveals a repetitive malfunction unstable, and temperature readings discrepancy actual value of the control system.

How to cite

Гудков А.Г., Чечёткин А.В., Лазаренко М.И., Леушин В.Ю., Бобрихин А.Ф., Маржановский И.Н., Борозинец А.С., Лемонджава В.Н. Использование современного оборудования для обеспечения безопасности тромбоцитного концентрата в учреждениях службы крови // Технологии живых систем. 2016. № 4. С. 50–56.

References

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[1] Cybuljak G.N., CHechetkin A.V. Infuzionno-transfuzionnaja terapija // Obshhaja khirurgija povrezhdenijj: Rukovodstvo dlja vrachejj. SPb.: Gippokrat. 2005. S. 148-185.

[2] Gricaev S.V., Glazanova T.V., Davaasambuu B. i dr. EHffektivnost transfuzijj trombocitokoncentrata i antitrombocitarnye i antilejjkocitarnye antitela u bolnykh ostrym mieloidnym lejjkozom pri provedenii intensivnojj citostaticheskojj terapii // Vestnik sluzhby krovi Rossii. 2014. № 2. S. 46-51.

[3] Goodrich R.P., Edrich R.A., Li J., Seghatchian J. The Mirasol PRT system for pathogen reduction of platelets and plasma: an overview of current status and future ternds // Transf, Apheres, Sci. 2006. V. 35. № 1. P. 5-17.

[4] Vasconcelos E., Oliveira I., Maria V. Bacterial screening through the use of a sampling pouch: how far is it representative of a platelet component - // Vox Sang. 2014. V. 107. Suppl. 1. R. 107-108

[5] Osselaer C.A.C., Defoin L., Doyen C. Intercept for pathogen inactivation (PI) in platelet concentrates (PC) effectively prevents transfusion associated graft-versus-host diseas (TA-GVHD) // Vox. Sang. 2010. V. 99. Suppl. 1. P. 428.

[6] Goodrich R.P., Edrich R.A., Li J., Seghatchian J. The Mirasol PRT system for pathogen reduction of platelets and plasma: an overview of current status and future ternds // Transf, Apheres, Sci. 2006. V. 35. № 1. P. 5-17.

[7] Salado W., Sumian C., Dehaut F., Begue S. In vitro evaluation of platelet concentrates pathogen reduced with theraflexuv-platelets procedure // Vox Sang. 2014. V. 107. Suppl. 1. P. 129.

[8] Bobrikhin A.F., Gudkov A.G., Leushin V.JU., Lemondzhava V.N., Petrov V.I., SHHukin S.I. Oborudovanie dlja teplovojj obrabotki i khranenija komponentov i preparatov krovi // Medicinskaja tekhnika. 2015. № 2. S. 40-43.

[9] Bobrikhin A.F., Borozinec A.S., Lemondzha- va V.N., Leushin V.JU., Marzhanovskijj I.N. Ustrojjstvo dlja bezopasnogo khranenija trombocitosoderzhashhikh transfuzionnykh sred s ispolzovaniem informacionnykh i RCHID tekhnologijj // Materialy konferencii «SVCH-tekhnika i telekommunikacionnye tekhnologii». 6-12 sentjabrja 2015.

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