Article or book title, author's surname, DOI

Saccadic eyes movements in patients with Parkinson's disease untreated

Н.А. Рябчикова1, Е.В. Дамянович2, Л.А. Чигалейчик3, Б.Х. Базиян4

research article UDC 612.846.1:376 Pages: 61-65

  1. 1 д.б.н., ст. науч. сотрудник, кафедра высшей нервной деятельности, биологический факультет, Московский государственный университет им. М.В. Ломоносова
  2. 2,3 к.м.н., ст. науч. сотрудник, лаборатория нейрокибернетики, Научный центр неврологии (Москва)
  3. 4 д.б.н., зав. лабораторией нейрокибернетики, Научный центр неврологии (Москва)

Abstract

Parkinson’s disease (PD) is a slowly grow progressively neurodegenerative disease of the nervous system. It manifests tremor, hypokinesias, muscular rigidity, postural instability. In most cases, patients with PD have violations of cognitive functions. The process of prognosis the appearance of the events is one of the cognitive brain functions underlying of the human intellectual activity. Numerous studies have shown that cognitive processes (attention, memory, thinking) accompanied by saccadic eye movements. Moreover, the cognitive processes are often complicated without those movements. Functional and anatomical overlapping of brain structures (frontal and parietal cortex areas, basal ganglia) provides, on the one hand, the process of planning, programming and decision-making, on the other – the control of saccades generation. 

How to cite

Рябчикова Н.А., Дамянович Е.В., Чигалейчик Л.А., Базиян Б.Х. Взаимосвязь саккадических движений глаз и когнитивных процессов пациентов с ранними стадиями болезни Паркинсона // Нейрокомпьютеры: разработка, применение. 2017. № 4. С. 61–65.

References
  1. Aarsland D., Andersen K., Larsen J.P. Prevalence and characteristics of dementia in Parkinson’s disease: an 8-year prospective study // Arch. Neurol. 2003. V. 60. P. 387–392. 
  2. Brown R.G., Marsden C.D. How common is dementia in Parkinson’s disease? Lancet, 1984. V.2. P. 1262–1265.
  3. Cummings J.L. Intellectual impairments in Parkinson’s disease: clinical, pathological and biochemical correlates // J. Ger. Psych. Neurol. 1988. № 1. P. 24–36.
  4. Bazyian B.Kh., Chigaleichik L.A., Dmitriev I.E. Possible mechanisms of disorders of saccadic eye movements in patients with Parkinson's disease // Bull. Exp. Biol. Med. V. 125. № 3. P. 254–259. 
  5. Baziyan B.Kh., Chigaleichik L.A., Teslenko E.L., Damjanovich E.V., Shvetsov A.Yu., Ivanova E.A., Ivanova-Smolenskaya I.A., Illariushkin S.N. Disorders of arbitrary hand-eye movements of patients with early stages of Parkinson's disease // Neurology and Neurosurgery in Belarus. 2011. V. 10. № 2. P. 65–81.
  6. Ryabchikova N.A. Baziyan B.Kh., Polyansky V.B., Pletnev O.A. the Role of saccadic eye movements in cognitive processes // Bull. Exp. Biol. and Honey. M.: 2009. V. 147. № 1. P. 11–14.
  7. Moskalenko Y.E., Ryabchikova N.A., Halvorson W., Vardy T.C. Changes of Circulatory – Metabolic Indices and Skull Biomechanics with Brain Activity During Aging // Journal of Integrative Neuroscience. Transdisciplinary Journal, Imperial College Press. 2011. V. 10. № 2. P. 131–160.