Diagnostic conformal system for brain neuroimaging by using a multichannel radio thermometer based on monolithic integrated circuits

М.К. Седанкин; С.Г. Веснин; В.Ю. Леушин; С.В. Агасиева; С. В. Чижиков; В.В. Назаров; Л.Ю. Мершин; А.А. Коновалова; И.В. Нелин; В.А. Скуратов

doi:10.18127/j22250980-202001-05

Diagnostic conformal system for brain neuroimaging by using a multichannel radio thermometer based on monolithic integrated circuits

М.К. Седанкин¹, С.Г. Веснин², В.Ю. Леушин³, С.В. Агасиева⁴, С. В. Чижиков⁵, В.В. Назаров⁶, Л.Ю. Мершин⁷, А.А. Коновалова⁸, И.В. Нелин⁹, В.А. Скуратов¹⁰

research article UDC 615.471 Pages: 43-61 doi.org/10.18127/j22250980-202001-05

¹ к.т.н., ст. науч. сотрудник, НИИ радиоэлектроники и лазерной техники, МГТУ им. Н.Э. Баумана; ФГБУ ГНЦ РФ «Федеральный медицинский биофизический центр им. А.И. Бурназяна» ФМБА России
² к.т.н., ст. науч. сотрудник, НИИ радиоэлектроники и лазерной техники, МГТУ им. Н.Э. Баумана; гл. конструктор, ООО «РТМ Диагностика» (Москва)
³ к.т.н., ст. науч. сотрудник, НИИ радиоэлектроники и лазерной техники МГТУ им. Н.Э. Баумана; зам. генерального директора, ООО «НПИ ФИРМА «ГИПЕРИОН» (Москва)
⁴ к.т.н., доцент, Российский университет дружбы народов (Москва); ст. науч. сотрудник, НИИ радиоэлектроники и лазерной техники МГТУ им. Н.Э. Баумана
⁵ аспирант, МГТУ им. Н.Э. Баумана; мл. науч. сотрудник, НИИ радиоэлектроники и лазерной техники МГТУ им. Н.Э. Баумана; техник, ЦМИТ «Куб» (Москва)
⁶ к.т.н., доцент, МГТУ им. Н.Э. Баумана
⁷ студент, кафедра оптических и биотехнических систем и технологий, ФГБУ ВО «МИРЭА – Российский технологический университет»; мл. науч. сотрудник, ФГБУ ГНЦ РФ «Федеральный медицинский биофизический центр им. А.И. Бурназяна» ФМБА России (Москва)
⁸ аспирант, кафедра оптических и биотехнических систем и технологий, ФГБУ ВО «МИРЭА – Российский технологический университет»
⁹ к.т.н., доцент, кафедра «Радиолокация, радионавигация и бортовое радиоэлектронное оборудование», Московский авиационный институт
¹⁰ науч. сотрудник, АО «Всероссийский научно-исследовательский институт радиотехники» (Москва)

Keywords: Neurohelmet conformal antenna system microwave radiometry brain neuroimaging

Abstract

Statement of the problem. The development of a conformal diagnostic system (neurohelmet) based on a multichannel radio thermometer developed using monolithic integrated circuits and operating in a wide frequency band of 3.4-4.2 GHz will allow the creation of medical devices that allow functional diagnostics of the brain.

Aim of the work. To consider the option of constructing a diagnostic conformal antenna system for brain neuroimaging.

Results. A construction option for a multi-channel radio thermometer using monolithic integrated circuits, implemented as a conformal diagnostic system (neurohelmet), is proposed. Printed slot antennas are made of flexible dielectric material used in the manufacture of printed circuit boards. Antennas are connected to a miniature radiometer, which is located in the center of the antenna system. Antennas are switched by the switch integrated with a radiometer in a single module. A conformal multichannel antenna system ensures the fit of flexible antennas to the human head.

Practical significance. Studies have shown the possibility of using multichannel microwave radiometry to detect brain diseases. The method makes it possible to detect thermal abnormalities of the brain and conduct its thermal monitoring. The foundation has been laid for creating a prototype of a multi-channel microwave radiometer based on monolithic integrated circuits.

How to cite

Седанкин М.К., Веснин С.Г., Леушин В.Ю., Агасиева С.В., Чижиков С.В., Назаров В.В., Мершин Л.Ю., Коновалова А.А., Нелин И.В., Скуратов В.А. Диагностическая конформная система для нейровизуализации головного мозга с использованием многоканального радиотермометра на основе монолитных интегральных схем // Нанотехнологии: разработка, применение - XXI век. 2020. № 1. С. 43–61. DOI: https://doi.org/10.18127/j22250980-202001-05

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[1] Machinskij P.A. i dr. Sravnitel'naya harakteristika pokazatelej zabolevaemosti ishemicheskim i gemorragicheskim insul'tom v Rossii. Izv. vuzov. Povolzhskij region. Medicinskie nauki. 2019. № 2 (50). C. 112–132.

[2] Gudkov A.G., Leushin V.Yu., Sidorov I.A., Vesnin S.G., Sedankin M.K. i dr. Informacionno-izmeritel'nye i upravlyayushchie radioelektronnye sistemy i kompleksy: Monografiya. Pod. red. V.S. Verby. M.: Radiotekhnika. 2020. 490 s., il. (Nauch. seriya «Trudy nauchnyh shkol AO «Koncern «Vega»).

[3] Gudkov A.G., Leushin V.Yu., Agasieva S.V. i dr. Povyshenie nadezhnosti i kachestva GIS i MIS SVCH. Kn. 3. Pod red. V.N. V'yuginova, A.G. Gudkova i V.V. Popova. M.: OOO NTP «Virazh-Centr». 2016. 252 s.

[4] Vesnin S.G., Sedankin M.K., Pashkova N.A. Matematicheskoe modelirovanie sobstvennogo izlucheniya golovnogo mozga cheloveka v mikrovolnovom diapazone. Biomedicinskaya radioelektronika. 2015. № 3. S. 17–32.

[5] Vesnin S.G., Sedankin M.K. Sravnenie mikrovolnovyh antenn-applikatorov medicinskogo naznacheniya. Biomedicinskaya radioelektronika. 2012. № 10. S. 63–74.

[6] Sedankin M.K., Leushin V.Yu., Gudkov A.G., Vesnin S.G., Sidorov I.A., Agasieva S.V., Markin A.V. Matematicheskoe modelirovanie teploobmennyh processov v molochnoj zheleze pri nalichii zlokachestvennoj opuholi. Medicinskaya tekhnika. 2018. № 3S (309). S. 33–36.

[7] Sedankin M., Chupina D., Vesnin S., Nelin I., Skuratov V. Development of a miniature microwave radiothermograph for monitoring the internal brain temperature. Vostochno-Evropejskij zhurnal peredovyh tekhnologij. 2018. № 3 (5). P. 26–36.

[8] Chupina D.N., Sedankin, M.K., Vesnin S.G. Application of modern technologies of mathematical simulation for the development of medical equipment. In 2017 IEEE 11th International Conference on Application of Information and Communication Technologies (AICT). P. 1–5.

[9] Gulyaev Yu.V., Leushin V.Yu., Gudkov A.G., SHCHukin S.I., Vesnin S.G., Kublanov V.S., Porohov I.O., Sedankin M.K., Sidorov I.A. Pribory dlya diagnostiki patologicheskih izmenenij v organizme cheloveka metodami mikrovolnovoj radiometrii. Nanotekhnologii: razrabotka, primenenie XXI vek. 2017. № 2. S. 27–45.

[10] Sedankin M.K., Leushin V.YU., Gudkov A.G., Vesnin S.G., Sidorov I.A., Agasieva S.V., Ovchinnikov L.M., Vetrova N.A. Antenny-applikatory dlya medicinskih mikrovolnovyh radiotermografov. Medicinskaya tekhnika. 2018. T. 4. № 310. S. 13–15.

[11] Sedankin M.K., Leushin V.YU., Gudkov A.G., Vesnin S.G., Hromov D.A., Porohov I.O., Sidorov I.A., Agasieva S.V, Gorlacheva E.N. Matematicheskoe modelirovanie sobstvennogo teplovogo izlucheniya pochki v mikrovolnovom diapazone. Medicinskaya tekhnika. 2019. № 1. S. 44–47.

[12] Sedankin M.K., Gudkov A.G., Leushin V.Yu., Vesnin S.G., Sidorov I.A., CHupina D.N., Agasieva S.V., Skuratov V.A., CHizhikov S.V. Mikrovolnovaya radiotermometriya organov malogo taza. Medicinskaya tekhnika. 2019. № 4. S. 45–49.

[13] Butrov A.V., SHevelev O.A., CHeboksarov D.V. Teplovoj balans mozga pri cerebral'nyhkatastrofah i korrekciya ego narushenij metodom terapevticheskoj gipotermii. M.: OOO «Mediamed». 2014. 14 s.

[14] SHevelev O.A. i dr. Vozmozhnosti kraniocerebral'noj gipotermii i radiotermokartirovaniya dlya diagnostiki i lecheniya ostrogo narusheniya mozgovogo krovoobrashcheniya. Zdorov'e i obrazovanie v XXI veke. 2014. T.16. № 2. S. 42–43.

[15] Mobashsher A.T., Abbosh A.M. On-site rapid diagnosis of intracranial hematoma using portable multi-slice microwave imaging system. Scientific Reports.6:37620. DOI: 10.1038/srep37620. P. 1–17.

[16] Mobashsher A.T., Abbosh A.M. Developments of tomography and radar-based head imaging systems. Proc. Inter. Symp. Antennas Propag. P. 1–3. 2015.

[17] Oficial'nyj sajt TheAccuCorDTMS, http://www.thermimage.com/news/15.

[18] Patent RF № 2673103. Tekstil'naya antenna dlya mikrovolnovoj radiotermometrii. S.G. Vesnin, H.SH. Tahir, S. Navnit, M.K. Sedankin.

[19] Sedankin M.K et. al. Development of patch textile antenna for medical robots. In 2018 International Conference on Actual Problems of Electron Devices Engineering (APEDE) (pp. 413-420). IEEE.

[20] Leushin V., Chizhikov S., Vesnin S. , Sedankin M., Porokhov I., Gorbachev D., Gorlacheva E. Numerical simulation of miniature antennas applicators of microwave radiometry for diagnostics of the functional state of the brain. ITM Web of Conferences. EDP Sciences. 2019. V 30. № 13005. P. 7.

[21] Stauffer P.R., Rodrigues D.B., Maccarini P. Utility of microwave radiometry for diagnostic and therapeutic applications of non-invasive temperature monitoring. Conference paper: IEEE Ben MAS 2014, At Philadelphia, PA. DOI: 10.13140/2.1.3762.0487.

[22] Stauffer P.R. et al. Stable microwave radiometry system for long term monitoring of deep tissue temperature. Proc SPIE. 2013. February 26; 8584:doi:10.1117/12.2003976 [Elektronnyj resurs] http://proceedings.spiedigitallibrary.org/ on 04/22/2013 terms of use: http://spiedl.org/terms

[23] Non-invasive measurement of brain temperature with microwave radiometry: demonstration in a head phantom and clinical case/ P.R. Stauffer[et al.]// The Neuroradiology Journal 27: 000-000, 2014. P. 51–60.

[24] Vesnin S., Sedankin M., Ovchinnikov L., Leushin V., Skuratov V. et. al. Research of a microwave radiometer for monitoring of internal temperature of biological tissues. Eastern-European Journal of Enterprise Technologies. 2019. V. 4. № 5 (100). P. 6–15.

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