Article or book title, author's surname, DOI

Artificial intelligence in flow cytometry systems: a method to increase the processing speed of big data. Problems and solutions

V.G. Nikitaev1, T.G. Gevorkyan2, A.N. Pronichev3, T.N. Zabotina4, O.V. Nagornov5, E.B. Vesna6, A.A. Borunova7, M.S. Torosyan8

research article UDC 004.75 Pages: 50-54 doi.org/10.18127/j15604136-202603-08

  1. 1,3,5,6,8 National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), (Moscow, Russia)
  2. 2,4,7 Blokhin National Research Medical Center of Oncology, Ministry of Health of the Russian Federation, (Moscow, Russia)

Abstract

The development of the paper addresses the interdisciplinary challenge of accelerating data processing for flow cytometry. Traditional use of the pandas library in Python is limited by sequential calculations: processing 500 000 leukocyte cells takes 15 seconds. This long waiting time causes user discomfort and may lead to medical errors.

The aim of the study is to develop an original method for increasing processing speed using parallel calculations, building on the authors’ previous work on leukocyte population recognition. The approach employs algorithms from the Ray distributed computing framework and the modin. pandas library. Experiments on clinical laboratory equipment confirm the solution’s effectiveness compared to traditional pandas algorithms.

The use of the developed method reduced the processing time for 500 000 cells by 11 times, using data from an open Internet source. The method is scalable for medical diagnostics, treatment, forecasting, and artificial intelligence systems.

Received
05.02.2026
Approved after review
09.02.2026
Accepted
31.03.2026

How to cite

Никитаев В.Г., Геворкян Т.Г., Проничев А.Н., Заботина Т.Н., Нагорнов О.В., Весна Е.Б., Борунова А.А., Торосян М.С. Искусственный интеллект в системах проточной цитометрии: метод увеличения скорости обработки больших данных. Проблемы и решения // Биомедицинская радиоэлектроника. 2026. T. 29. № 3. С. 50−54. DOI: https:// doi.org/10.18127/j156 04136-202603-08

References
  1. Nikitaev V.G., Zabotina T.N., Pronichev A.N., Borunova A.A., Torosyan M.S. Metod raspoznavaniya grupp lejkocitov po rezul'tatam protochnoj citometrii.  Medicinskaya tekhnika. 2026. № 1. S. 10–12 (In Russian).
  2. Balalaeva I.V. Protochnaya citofluorimetriya: Uchebno-metodicheskoe posobie. Nizhnij Novgorod: Nizhegorodskij gosuniversitet, 2014. 75 s. (In Russian).
  3. Orekhov A.V., Shishkin V.I., Kudryavceva G.V., Pavilajnen G.V., Shishkin V.V., Lyudkevich N.S. Avtomaticheskoe poluchenie «uproshchennoj lejkocitarnoj formuly» metodami protochnoj citofluorimetrii i klasternogo analiza.  Vestnik SPbGU. Prikladnaya matematika. Informatika. 2023. T. 19. № 4. S. 69–483 (In Russian).
  4. Kissler M.J., Porter S., Knees M., Kissler K., Keniston A., Burden M. Attention Among Health Care Professionals: A Scoping Review. Annals of Internal Medicine. 2024. V. 177. № 7. P. 941–952.
  5. Nikitaev V.G., Pronichev A.N., Nagornov O.V., Sergeev V.Yu., Kozyreva A.V. Mezhdisciplinarnaya model' pigmentnoj seti na dermatoskopicheskih izobrazheniyah v priborah diagnostiki zabolevanij kozhi. Biomedicinskaya radioelektronika. 2025. T. 28. № 5. S. 14–17 (In Russian).
  6. Gafarov F.M., Galimyanov A.F. Parallel'nye vychisleniya: uchebnoe posobie. Kazan': Kazanskij universitet. 2018. 149 s. (In Russian)
  7. Flow Cytometry datasets consisting of peripheral blood and bone marrow samples for the evaluation of explainable artificial intelligence methods [Электронный ресурс]. Mendeley Data. URL: https://data.mendeley.com/datasets/jk4dt6wprv/1 (дата обращения: 14.02.2026).