The concept of the quantitative theory of homeostasis in relation to the assessment of changes in the aerobic efficiency of a person after being in the conditions of 17-day isolation (SIRIUS-17)

For the first time, an attempt was made to describe the process of transition of a biological system from one state to another, using fractal dimension, using as an example changes in body functions in response to physical exertion.

The proposed approach reveals the concept of the integrity of the organism, its spatial and temporal definiteness and the multifactorial nature of interaction with the environment. The experiment involved 6 physically healthy volunteers, whose average age was 35 ± 6 years. All examinations were carried out before and after the isolation experiment. Changes in aerobic performance were assessed using locomotor test results, which ran from 5 to 2 days before isolation and on the first or second day after its completion. When performing the test before, during and after the load, the following were recorded: oxygen consumption and carbon dioxide emission, pulmonary ventilation (Oxycon Mobile gas analyzer), heart rate (Cardiocassette 2010). Indicators of the main component in the running speed range could take positive and negative values, and also that the speed at which the indicators of the main component began to take negative values may differ in tests before and after isolation. It can be assumed that volunteers who have registered the moment of transition from the positive to the negative area of the main components have a higher level of aerobic capacity of the organism, in this connection, and in energy supply systems. Thus, we come to the understanding that the fractal dimension characterizes the properties of the physiological system to maintain homeostasis under the influence of various environmental factors, the ability to maintain or change its response to external influences.