fMRT ultrafast sequence for study the human brain cogni-tive functions
- 1 к.б.н., вед. науч. сотрудник, отдел нейрокогнитивных технологий, Курчатовского комплекса НБИКС-технологий, Национальный Исследовательский Центр «Курчатовский институт» (Москва)
- 2,4 аспирант, инженер-исследователь, отдел нейрокогнитивных технологий Курчатовского комплекса НБИКС-технологий, Национальный Исследовательский Центр «Курчатовский институт» (Москва)
- 3 инженер-исследователь, отдел нейрокогнитивных технологий Курчатовского комплекса НБИКС-технологий, Национальный Исследовательский Центр «Курчатовский институт» (Москва)
- 5 д.псих.н., заместитель директора Курчатовского комплекса НБИКС-технологий, Национальный Исследовательский Центр «Курчатовский институт» (Москва)
Abstract
In this paper we compared the motor functions localization in the human brain using the analysis of fMRI data obtained by the standard (TR = 2 s) and ultra (TR = 0.3 s) fMRI sequence. The study involved 14 healthy volunteers between the ages of 19 to 24 (average age 21.5). Magnetom Verio 3T (Siemens, Germany) with 32-channel head coil was used for MRI data acquisition. fMRI protocol for ultrafast sequence was obtained from the University of Minnesota Center for Magnetic Resonance Research.
The experiment consisted of 3 different sessions:
1. Standard EPI-based protocol for functional data acquisition (TR = 2000 ms, TE = 20 msec, slices 42, voxel size 2x2x2 mm) in the block paradigm (3 blocks of 10 s of right hand finger tapping).
2. Ultrafast protocol for functional data acquisition (TR = 300 ms, TE = 25 ms, 42 slice, the size of the voxel 2x2x2 mm) in the same paradigm (3 blocks of 10 s of right hand finger tapping).
3. Ultrafast protocol with the same parameters for event-related paradigm (2 times rapid right hand grip into a fist, 8 repetitions lasting 1 s and 10,5 s of rest between iterance).
Shown, that the standard and ultrafast fMRI protocols have a high level of compliance with the published results for brain activity (corresponding to sensomotor functions) spatial localization. This opens up the possibility of using selected ultra-fast sequence for obtaining high spatial or temporal resolution of fMRI data in subsequent neurocognitive studies. It could be extremely useful for super-fast neuro interfaces with the high spatial resolution development namely for event-related designed experiments and with simultaneously recording of fMRI, EEG, verbal and tactile responses as well as the eye-tracking data.
How to cite
Ушаков В.Л., Орлов В.А., Зинченко В.В., Карташов С.И., Величковский Б.М. Ультрабыстрые последовательности фМРТ для ис-следования когнитивных функций головного мозга человека // Биомедицинская радиоэлектроника. 2017. № 2. С. 52–56.
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