The non-invasive laser speckle-sensor of blood flow velocity in microvasculature

The purpose of this study was developing and producing a laboratory model of individual speckle-sensor of blood flow velocity in microvasculature in human-s skin. Topicality of this paper is determined by the necessity of producing an individual sensor allowing well-timed registration of urgent situations in cardiovascular system of a patient. In order to achieve that there were posed the following problems: producing of the sensory part of the sensor; development of the informative signal processing system based on PC.

In order to accomplish a task there were discussed and examined various settings-up of sensory part of the sensor: a single-channel set-up, a set-up with two spatially distributed registering photo detectors. Besides there were discussed various methods of informative signal processing: autocorrelation and cross-correlation approaches. The processing of received data was organized using especial computer-based program made by means of LadVIEW.

As a result, there was developed and proved the methodology of non-invasive registration of average blood flow velocity in microvasculature based on speckle-interferometry. There was the laboratory model of the speckle-sensor of blood flow velocity in microvasculature produced. Efficiency of the model was demonstrated experimentally on patterns as well as in vivo.