E.N. Chuyan1, M.Yu. Ravaeva2, I.S. Mironyuk3, E.R. Dzheldubaeva4, I.V. Cheretaev5, S.Yu. Liventsov6

1–6 Institute of Biochemical Technologies, Ecology and Pharmacy
of the FSAEI HE “V.I. Vernadsky Crimean Federal University” (Simferopol, Republic of Crimea, Russia)

1 elena-chuyan@rambler.ru, 2 ravaevam@yandex.ru, 3 psevdoallelizm@mail.ru, 4 delviza@mail.ru, 5 cheretaev86@yandex.ru, 6 stas_liventsov@mail.ru

One of the urgent problems in biology and medicine is the influence of electromagnetic radiation (EMR) on biological objects. Due to the high biological and therapeutic activity, currently a lot of attention of physicians and biologists is attracted by EMR of the millimeter (mm) or extremely high-frequency (EHF) range with a wavelength in the free space of 1...10 mm, a frequency range of 300...30 GHz, maximum quantum energy 1,17·10 –3 eV and low intensity (power flow density (PFD) less than 10 MW/cm2).

The majority of human and animal diseases, for the treatment of which the action of low-intensity EHF EMR is directed, are accompanied by microhemodynamic disorders. However, the data of clinical and experimental studies on the effect of low-intensity EHF EMR on microcirculation processes are often ascertaining, and sometimes contradictory.

Objective – systematization, generalization, and deepening of up-to-date information on changes in MC processes in humans and experimental animals under the influence of low-intensity EHF EMR and presentation a concept with mechanism of action of this physical factor on tissue MHD. This will make it possible to use EHF therapy more effectively for the prevention and treatment of microcirculatory disorders.

The article examines modern ideas about changes in microcirculation processes in humans and experimental animals when exposed to low-intensity electromagnetic radiation of millimeter or extremely high frequency range (EHF EMR) based on the analysis of scientific literature and long-term own experimental studies. An original concept of mechanism action this physical factor on microhemodynamics is proposed.

The presented data make it possible to significantly expand the understanding of biological action mechanisms of low-intensity electromagnetic radiation in the millimeter range and to use EHF therapy more effectively for the prevention and treatment of microcirculatory disorders.

Chuyan E.N., Ravaeva M.Yu., Mironyuk I.S., Dzheldubaeva E.R., Cheretaev I.V., Liventsov S.Yu. Tissue microhemodynamics: mechanisms of influence of low-intensity electromagnetic radiation of the millimeter range. Technologies of Living Systems. 2024. V. 21. № 1. Р. 29-45. DOI: https://doi.org/10.18127/j20700997-202401-03 (In Russian)

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