M.S. Burdyukov - Ph.D. (Med.), Senior Research Scientist, N.N. Blokhin Russian Cancer Research Center (Moscow, Russia); Associate Professor, Department of Endoscopy, Russian Medical Academy of Postgraduate Education of Russian Ministry of Healthcare M.I. Davydov - Academician of RANS, Dr.Sc. (Med.), Professor, Director of Russian Cancer Research Center of N.N. Blokhin (Moscow, Russia) A.M. Nechipay - Dr.Sc. (Med.), Professor, Head of Science Department of Endoscopy of Russian Medical Academy of Postgraduate Education of Russian Ministry of Healthcare I.N. Yurichev - Endoscopist, N.N. Blokhin Russian Cancer Research Center (Moscow); Assistant, Department of Endoscopy, Russian Medical Academy of Postgraduate Education of Russian Ministry of Healthcare B.I. Dolgushin - Member-Correspondent of Russian Academy of Sciences, Dr.Sc. (Med.), Professor, Head Diagnostic Radiology Department, N.N. Blokhin Russian Cancer Research Center (Moscow, Russia) G.V. Ungiadze - Dr.Sc. (Med.), Professor, Head of Department of Endoscopy, N.N. Blokhin Russian Cancer Research Center (Moscow, Russia)

Endoscopic Ultrasonography (EUS) and Endoscopic Ultrasonography with Fine-Needle Aspiration (EUS-FNA) as an invasive methods are associated with a chance of adverse events. The unique properties of the echoendoscop and its ability to acquire tissue outside of the gastrointestinal lumen impart risks that are not associated with routine endoscopic proce-dures. Increased risks are connected to the safety of the needle insertion route, presence of blood disorders in patient etc. In this review we discuss frequency of adverse events related to EUS-FNA of solid masses. Evaluated the complications related to EUS and EUS-FNA procedures in analyzed a 10-year trend (2006-2016). In a retrospective single-center case-series, 1241 men and 1059 women, a total of 2300 patients (median age, 58 years), undergoing diagnostic EUS were included. Among a small cohort of 581 (25.3%) patients, EUS-FNA was applied. Adverse events associated with the procedure were reported in 6 (0.26% out of total EUS, n=2300) of cases, out of them 5 cases were related to EUS-FNA (0.52% out of total EUS-FNA, n=581).Among them 1 esophageal perforation (0,043% out of total EUS, n=2300), 2 cases of bleeding (0.086% out of total EUS, n=2300; 0.34% out of total EUS-FNA, n=581), 3 cases of infectious complications (0.13% out of total EUS, n=2300; 0.52% out of total EUS-FNA, n=581) were reportedly revealed. EUS and EUS-FNA have emerged is a generally safe and effective modality. However, adverse events do develop. Knowledge of potential complications secondary to EUS and EUS-FNA,their expected frequency, and their associated risk factors may help to minimize their occurrence.

 

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