E.A. Ovcharenko - Junior Research Scientist, Research Institute for Complex Issues of Cardiovascular Diseases under the Siberian Branch of the Russian Academy of Medical Sciences. E-mail: ov.eugene@gmail.com K.U. Klyshnikov - Junior Research Scientist, Research Institute for Complex Issues of Cardiovascular Diseases under the Siberian Branch of the Russian Academy of Medical Sciences. E-mail: Klyshnikovk@gmail.com T.V. Glushkova - Ph.D. (Biol.), Research Scientist, Research Institute for Complex Issues of Cardiovascular Diseases under the Siberian Branch of the Russian Academy of Medical Sciences. E-mail: bio.tvg@mail.ru A.U. Burago - Ph.D. (Med), Senior Research Scientist, Research Institute for Complex Issues of Cardiovascular Diseases under the Siberian Branch of the Russian Academy of Medical Sciences. E-mail: buraau@kem.cardio.ru I.U. Zhuravleva - Dr.Sc. (Med), Professor, Research Institute for Complex Issues of Cardiovascular Diseases under the Siberian Branch of the Russian Academy of Medical Sciences. E-mail: juravl_irina@mail.ru

Aim of the study: Analysis of the mechanical properties and further material selection of the human aortic root material model by finite element method. The results of aortic valve diseases correction, particularly prosthesis implantation, largely determine by properties of the aortic root: degree of calcification, elasticity and resilience. Current methods for predicting the outcome and effectiveness of such corrections is mainly based on biomechanical models of such systems: a number of studies devoted to the analysis of the mechanical properties of the aorta. However, the development of such methods, particularly finite element analysis, requires complex non-linear material models of the aortic root. To this end we have investigated «stress-strain» curves of aortic annulus and the sinotubular junction zones of human aortic root. Also the ultimate tensile strength and strain were measured. The resulting curves are presented as linear, quadratic and cubic approximation. It was shown that the samples collected from the site of the annulus statistically different from the sinotubular junction samples from the point of mechanical characteristics. Finite element computer analysis of the behavior of the aortic root in the «diastole-systole» cycle using the obtained models demonstrated the advantages of non-linear approach. Thus, in the result we suggest the using of nonlinear material models of the aortic root during a numerical simulation. Additionally, was sown that mechanical properties of the aortic annulus samples require the separate description of the material in this section.

 

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