350 rub
Journal Technologies of Living Systems №3 for 2013 г.
Article in number:
Cytokines in blood serum in patients with bone tumors
Keywords: bone tumors cytokines
Authors:
I.V. Babkina, I.N. Kuznetsov, Russo E.Yu., L.T. Liyakina, V.G. Degtiyar
Abstract:
Bone tumors in total cancers are relatively rare, the etiology and pathogenesis of bone tumors has not yet been studied. Achieved over the last two decades in improving the diagnosis and treatment of certain types of bone sarcomas, particularly osteosarcoma, unfortunately, last observations does not show improve long-term outcomes, possibly because of the inconsistency of joint international efforts to identify new targets and introduction of new methods of treatment. This article presents a review of the literature and the results of their own research cytokines: granulocyte-macrophage colony - stimulating factor (GM-CSF) and granulocyte colony stimulating factor (G-CSF), tumor necrosis factor (TNF-α), interferon-alpha (IFN-α) and - gamma (IFN-γ), interleukin -2 (IL-2), -6 (IL-6) and -16 (IL-16) in blood serum of patients with bone tumors prior specific treatment and healthy people. The role of cytokines in the pathogenesis of bone tumors are discussing.
Pages: 21-35
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