350 rub
Journal Technologies of Living Systems №7 for 2011 г.
Article in number:
Bone Tumors and Levels of Interferon α and γ in Blood Serum
Authors:
I.V. Babkina, N. E. Kushinsky, E.A. Ten, Yu.N. Soloviev, O.I. Kostileva, G.N. Machak, M.D. Aliev
Abstract:
Serum levels of interferon γ (IF-γ) in healthy people and in patients with benign bone neoplasms were significantly high to compare to borderline and malignant bone tumors. No reliable distinguishes were found between serum levels of IF-α in patients with benign, borderline and malignant bone tumors. Invert correlation were shown between age and serum level of IF-α in healthy people, on the contrary no correlations were observed between age and serum levels of IF-γ and of IF-α in patients with bone neoplasms. And also serum IF-γ and IF-α levels in patients with bone sarcomas are not depend on the tumors histology and on the size of primary bone tumors. No correlation was found in levels of IF-α and IF-γ in patients with localized and metastasizing tumor processes. Direct correlation was found between IF-α and IF-γ serum levels in patients with malignant bone tumors in condition of maximal IF-concentrations in blood serum and tumor process generalization
Pages: 45-50
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