N.U. Kelina, N.V. Besruchko

Technology of biochemical assessment for the endogen intoxication may by take to technology living system. The goal of this work - prove of meaning technology of biochemical assessment for the endotoxicose organism in the human ecology. Basis of technology of biochemical assessment the level endotoxicose appear to separation correlation of parameters oxidant, antioxidant system and middle molecules mass for foundation analysis calculated indexes, supply study of multitude regression of exponent middle molecules mass from gematological and clinical-biochemical tests. They be based to registration of deposit separate blocs of analysis tests (gematological and clinical-biochemical) and take of calculated in-dexes of markers parameters of heaviness endogen intoxication, demand on analysis frontier alte-ration with summary deviation of the norm laboratory tests in the dynamics, estimation criterion, correlation of standard indexes intoxication. Biochemical model to analysis health of people, basis to estimation of factors risk include bloc clinical-biochemical inspection of people, basis to program for the estimation of metabolism; bloc criterions of information meaning change analysis biochemical tests and calculated indexes, about referent sizes; bloc practice utilize of markers biochemical tests and calculated indexes for the problems of estimation of factors risk. By necessity of system analysis discover of influence toxicants to man organism may be realization basis to study correlations estimation criterions of expozition load and criterion in the discover frontier alteration with deviation of the norm parame-ters metabolism reaction, answer to this influence.