I.V. Radysh, T.V. Koroteeva

The article is devoted to study the chronostructure of seasonal changes of concentration macro- and microelements in blood plasma in the healthy women during the menstrual cycle. 195 practically healthy women aged 20-30 years during menstrual cycle and seasons of year is surveyed. The contents macro- and microelements (K, Na, Ca, Mg, P, Cr, Cu, Fe, Mn, Zn, Se) in blood plasma carried out by the atomic absorption spectrometry (ААS-1, Germany). Is established, that in the maximal meanings of concentration in blood plasma Na, Se and Zn were observed in the winter, Cr - spring, K, Ca, Mg, Р and Cu - summer, Fe and Mn - autumn, irrespective of the phases of menstrual cycle. Thus, the annual meaning of the concentration Ca, Na, Р, Fe, Cu, Zn and Mn significant higher (р < 0,05) in the mid-follicular phase, К, Mg, Se and Cr - in the mid-luteal are revealed. The amplitude of the seasonal rhythm of ratio Ca/Mg are surveyed in the mid-luteal phase significant higher (р < 0,05), than in the mid-follicular, that testifies to stability of monthly fluctu-ations of an exchange Ca and Mg, which grow in second half menstrual cycle. Thus, the received data testify to wavy adaptive changes of an element exchange during men-strual cycle. Thus the statistical significant seasonal changes parameters of the element exchange in the healthy women are revealed.