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Journal Technologies of Living Systems №1 for 2009 г.
Article in number:
Ultrasonic Peeling
Authors:
Gorshkova V. M.
Abstract:
Ultrasonic peeling can be referred to the surface peeling which is atraumatic because the corneal layer (dead cells) is peeled from the skin surface. A decrease in thickness of the corneal layer permits to remove hyperkeratosis regions, to increase living corneal layers thickness, to improve a skin tint (color) and to clear hyperpigmented regions. The ultrasonic peeling technology has been developed in the Bauman Moscow State Technical University. During ultrasonic peeling the ultrasonic vibration effect is produced on the system of a pharmaceutical substance in solution (gel, cream) (antiseptics or -hydroxy-acids of low concentration) and a biological tissue of the skin (corneal layer and epidermis). Flow characteristics of solutions can be shown as: , where  " shear stress;  " shear rate. Resting fluid, lying on the surface (corneal) skin layer is exposed to ultrasonic effect by means of an ultrasonic generator and a tool, which results in formation of microbubbles, i.e. cavitation. The presence of caverns makes fluid compressible. The latter means that its density depends on pressure. Hence, as a result of interaction of corneal layer cells and microbubbles, the latter collapse, therefore the overpressure (microlocal pressure) is created in the region of their effect, which results in peeling of dead (corneal layer) cells. Thus, the dynamic conditions of the bubble collapse have been found. Hence, as a result of interaction of corneal layer cells and microbubbles the latter collapse, therefore, in the region of ultrasonic effect the overpressure is created, which results in peeling of keratinized (dead) cells. It is known that the corneal layer is an unwettable surface. Note that a criterion for high quality peeling is wettability of surface, which can be described by the following conditions: let be surface tension at the skin-air interface, surface tension at the skin-solution interface, surface tension of solution-air, and contact angle. Condition of the surface wettability is as follows: If ? the surface is wettable, if ? the surface is unwettable. Therefore, upon carrying out the ultrasonic peeling the skin surface becomes wettable which permits to draw a conclusion about the efficiency of ultrasonic peeling
Pages: 48
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