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Journal Science Intensive Technologies №6 for 2025 г.
Article in number:
Practical aspects of using nuclear physics methods in medicine: the case of radiation therapy
Type of article: overview article
DOI: https://doi.org/10.18127/j19998465-202506-06
UDC: 615.849.1
Authors:

E.N. Lykova1, A.V. Nazarenko2, E.A. Novikova3, A.P. Chernyaev4, V.V. Rozanov5,
S.A. Gavrilova
6, F.R. Studenikin7, A.A. Shcherbakov8, E.V. Ivanov9, M.R. Akhmetshina10,
E.A. Kopylova
11

1,3–11 Lomonosov Moscow State University (Moscow, Russia)
1,2 Moscow Clinical Research Center named after A.S. Loginova (Moscow, Russia)
1 iv-kate@yandex.ru, 2 a.nazarenko@mknc.ru, 3 evgeniyanovikovazar@gmail.com, 4 a.p.chernyaev@yande.ru,
5 vrozanov@mail.ru, 6 sgavrilova@mail.ru, 7 studenikin@gmail.com, 8 sherbakov.aa15@physics.msu.ru,
9 ivanovev101@gmail.com, 10 marina2842@gmail.com, 11 ekaterinakalip@gmail.com

Abstract:

Modern medicine is currently undergoing active implementation of high-tech diagnostic and treatment methods, among which nuclear physics technologies hold a special place. These methods, based on the use of ionizing radiation, open new possibilities in the fight against oncological diseases, enabling highly precise targeting of pathological foci while minimizing damage to healthy tissues. Radiation therapy, as one of the key tools in radiation oncology, continues to evolve, offering increasingly advanced methods for delivering therapeutic doses of radiation.

The relevance of this work stems from the need to systematize modern approaches to planning and conducting radiation therapy, as well as the importance of disseminating knowledge about new technologies among medical professionals. The article provides a detailed examination of the practical applications of nuclear physics methods, ranging from the fundamental principles of medical accelerators to cutting-edge techniques such as 3D conformal therapy, intensity-modulated radiation therapy (IMRT), and volumetric modulated arc therapy (VMAT).

Pages: 53-70
For citation

Lykova E.N., Nazarenko A.V., Novikova E.A., Chernyaev A.P., Rozanov V.V., Studenikin F.R., Shcherbakov A.A. Practical aspects of using nuclear physics methods in medicine: the case of radiation therapy. Science Intensive Technologies. 2025. V. 26. № 6. P. 53−70. DOI: https://doi.org/ 10.18127/j19998465-202506-06 (in Russian)

References
  1. Chernyaev A.P., Lykova E.N., Borshchegovskaya P.Yu. Radiacionnaya medicinskaya fizika. M: Izd-vo MGU im. M.V. Lomonosova. 559 s. (in Russian).
  2. Klimanov V.A. Radiobiologicheskoe i dozimetricheskoe planirovanie luchevoj i radionuklidnoj terapii. Chast' 1. Radiobiologicheskie osnovy luchevoj terapii. Radiobiologicheskoe i dozimetricheskoe planirovanie distancionnoj luchevoj terapii: Ucheb. posobie. M.: NIYAU MIFI. 2011 (in Russian).
  3. Oficial'nyj sajt kompanii Varian [Elektronnyj resurs].URL: https://www.varian.com/en-au/products/radiosurgery/treatment delivery/hyperarc (in Russian).
  4. Chernyaev A.P., Rozanov V.V., Kozlova E.K. Vvedenie v medicinskuyu fiziku. M.: OOP fizicheskogo fakul'teta MGU. 81 s. (in Russian)
  5. Lykova E.N., Urazova K.A. Vvedenie v planirovanie luchevoj terapii puchkamitormoznyh fotonov: Ucheb. posobie. M.: OOP fizicheskogo fakul'teta MGU. 2019. 108 s. s il. (Ser.: Biblioteka medicinskogo fizika) (in Russian).
Date of receipt: 10.09.2025
Approved after review: 14.10.2025
Accepted for publication: 10.11.2025