V. F. Sazonov – Ph.D. (Biol.), Associate Professor, Department of Biology and Its Teaching Methods, Ryazan State University named after S.A. Esenin (Ryazan, Russia)

E-mail: kineziolog@mail.ru

I. V. Sazonov – Director, “Tri-W” Ltd. (Ryazan, Russia)

E-mail: mail@3w-site.ru

A. V. Grishaev – Post-graduate Student, Department of Ecology and Resource Using, Ryazan State University named after S.A. Esenin (Ryazan, Russia)

E-mail: ecology.ag@yandex.ru

In the article two different approaches to the analysis of changes in neuronal activity were counter opposed: structural and functional. The authors associate the structural approach with the concept of “plasticity” and the functional one with the concept of “regimity”. The conclusion is that the functional specification and neural network modeling and neural states of interneuron interactions make it possible to limit the functional approach to regime, abstracting from plastic structural rearrangements. The proposed regimity-functional approach is implemented in a series of computer programs “Impulsation” and “Neuroimpulsation”. These programs simulate interneuron relationships and visualise dynamics of neurons. The regimes of neurons and synapses thus systematized and described can be included in the terms of reference for developers of neurosimulators. Therefore, we set a task of studying the neurophysiological correspondence between the simulated virtual modes of “quasineurons” in computer models, and the actual neurons in the nervous system. Thus, we can assume that the use of the threshold principle in neuromodeling, supplemented by the mode of operation of neurons and synapses, can even more closely approximate the activity of imitation virtual “quasineuron” models of small neural networks to the work of real neural structures. The correctness, adequacy and relevance of neuromodels will be the higher, the more accurately they reproduce all the basic modes of operation of neurons and synapses and, in particular, those that are presented and described in this article.

Sazonov V.F., Sazonov I.V., Grishaev A.V. The concept of regimity in neuron work as a functional alternative to the structural plasticity in the computer simulation of interneuronal interactions. Neurocomputers. 2020. Vol. 22. No. 5. P. 43–53. DOI: 10.18127/j19998554-202005-04. (in Russian)

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