U.P. Mukha, L.G. Akulov, V.U. Naumov

Metrological support clinical diagnostic research is one of the most important problems that could provide high accuracy and reproducibility of the analysis. Full metrological analysis is possible, taking into account all the factors affecting the metrological experiment, so it is appropriate to introduce the concept bioinstrumental information-measuring system (BIMS). BIMS - is the measurement system, the structure of which consists of two subsystems: biotransformative input and instrumentally transformative intermediate signal. Input - is the impact of the environment on bio converter, intermediate signal - is output bio converter. Information flows of the system can derive the equation of measurement, based on which possible metrological analysis of the measurements.