350 rub
Journal №5 for 2014 г.
Article in number:
Studing of antioxidant properties of thiotriazolin in the simultaneous destruction of animals isoniazid, rifampicin, and hexavalent chromium compounds
Keywords: antioxidant properties isoniazid rifampicin hexavalent chromium compounds thiotriazoline
Authors:
N.I. Burmas - Assistant, of Department of General Chemistry, Ternopil State Medical University of I. Ya Gorbachevskiy Ternopil, Ukraine
L.S. Fira - Dr.Sc. (Biol.), Professor, Head of Department of Department of Pharmacy Postgraduate Education, Ternopil State Medical University of I. Ya Gorbachevskiy Ternopil, Ukraine
P.G. Lykhatskiy - Ph.D. (Biol.), Associate Professor, Department of Medical Biochemistry, Ternopil State Medical Universityof I. Ya Gorbachevskiy Ternopil, Ukraine
I.I. Gerasimets - Ph.D.(Pharm.), Associate Professor, Department of Pharmacy, Ternopil State Medical University of I. Ya Gorbachevskiy Ternopil, Ukraine
V.P. Pyda - Ph.D. (Pharm.), Associate Professor, Department of Pharmacology, Ternopil State Medical University of I. Ya Gorbachevskiy Ternopil, Ukraine
Abstract:
In studies in rats of different age groups found that by using Thiotriazoline poisoning animals compounds Cr6 + , isoniazid and rifampicin is marked reduction of free radical oxidation and the increase in the activity indicators of enzymatic and non-enzymatic units of the antioxidant system of the body, especially in animals immature and sexually mature age compared to affected rats. This demonstrates the strong antioxidant properties and possible applications Thiotriazoline it as a means of correcting for poisoning the body of heavy metals and toxic liver damage.
Pages: 44-49
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