350 rub
Journal №2 for 2014 г.
Article in number:
Distribution of insecticide Bankol in the blood and organs of rats with experimental intoxication
Keywords: insecticide Bankole dynamics content in the blood tropism organs
Authors:
V.A. Korolev - Dr.Sc. (Biol.), Professor, Department of Biology, Medical Genetics and Ecology, Kursk State Medical University, Russia. E-mail: medecol1@yandex.ru
V.K. Shormanov - Dr.Sc. (Chem.), Professor, Department of Pharmaceutical, Analytical Chemistry and Toxicology, Kursk State Medical University, Russia. E-mail: medecol1@yandex.ru
Y.D. Lyshev - Dr.Sc. (Med.), Professor, Department of Department of Pathological Physiology, Kursk State Medical University, Russia. E-mail: medecol1@yandex.ru
I.V. Gribach - Aspirant, Department of Biology, Medical Genetics and Ecology, Kursk State Medical University, Russia. E-mail: medecol1@yandex.ru
N.E. Kirischeva - Aspirant, Department of Biology, Medical Genetics and Ecology, Kursk State Medical University, Russia. E-mail: medecol1@yandex.ru
A.S. Podturkin - Student, Therapeutic faculty, Kursk State Medical University, Russia. E-mail: medecol1@yandex.ru
A.P. Kojaka - Student, Therapeutic faculty, Kursk State Medical University, Russia. E-mail: medecol1@yandex.ru
Abstract:
This article presents an assessment circulation of the insecticide Bankole in rats with acute intoxications. The dynamics of the quantitative content of the agricultural chemical in the blood was studied. It was set that the maximum absorption of the drug from the gastrointestinal tract into the blood in 6 hours after intragastric administration and the possibility to study the variability of biochemical, morphometric and physiological parameters of warm-blooded animals after the specified time. The tropism of organs was observed when it ingests to the investigated pesticide. Shown that hat the maximum extent (over 70%) affects the digestive organs of (stomach, intestines, liver) and excretory (kidney). This model of research allows to evaluate influence on the organism of ecological impact of small doses of pesticide which goes through trophic chains.
Pages: 66-70
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