350 rub
Journal №12 for 2014 г.
Article in number:
The study of the pharmaceutical market of drugs thyroid steps for the development of oral dosage forms
Keywords:
dry extract
Bugleweed European
Lycopus europaeus L.
herb
oral dosage form
action on the thyroid gland
Authors:
V.I. Zvereva - Post-graduate Student, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants, Moscow, Russia. E-mail: valentinca1988@mail.ru
E.I. Gribkova - Ph.D. (Pharm.), Senior Lecturer, Department of Management and Economics of Pharmacy, Peoples Friendship University of Russia, Moscow. E-mail: LenaIMK@yandex.ru
O.A. Semkina - Ph.D. (Pharm.), Leading Researcher, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants, Moscow, Russia; Associate Professor, Department of the General Pharmaceutical and Biomedical Technology, Peoples Friendship University of Russia, Moscow. E-mail: semkina@med.rudn.ru
Yu.M. Tertichnaya - Ph.D. (Pharm.), Leading Researcher, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants, Moscow, Russia. E-mail: vilarnii@mail.ru
Е.А. Nazarova - Post graduate Student, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants, Moscow, Russia. E-mail: vilarnii@mail.ru
N.B. Fadeev - Senior Research Scientist, Center for Applied Botany, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants, Moscow, Russia. E-mail: nfadeev@mail.ru
E.I. Gribkova - Ph.D. (Pharm.), Senior Lecturer, Department of Management and Economics of Pharmacy, Peoples Friendship University of Russia, Moscow. E-mail: LenaIMK@yandex.ru
O.A. Semkina - Ph.D. (Pharm.), Leading Researcher, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants, Moscow, Russia; Associate Professor, Department of the General Pharmaceutical and Biomedical Technology, Peoples Friendship University of Russia, Moscow. E-mail: semkina@med.rudn.ru
Yu.M. Tertichnaya - Ph.D. (Pharm.), Leading Researcher, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants, Moscow, Russia. E-mail: vilarnii@mail.ru
Е.А. Nazarova - Post graduate Student, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants, Moscow, Russia. E-mail: vilarnii@mail.ru
N.B. Fadeev - Senior Research Scientist, Center for Applied Botany, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants, Moscow, Russia. E-mail: nfadeev@mail.ru
Abstract:
Pharmaceutical market for drugs used in the prevention and treatment of diseases of the thyroid gland studied. The structure of the market of drugs in this therapeutic group defined. Investigational drugs are available in the following dosage forms: tablets, chewable tablets and tablets covered with a film cover. Most drugs registered and used in Russia, affecting the thyroid gland, are produced in Germany.Among registered drugs affecting the thyroid herbal medications are not available. During our studies, with the use of designed for these purposes, the questionnaire identified the segment of consumers of drugs in this group. It is mostly women aged 20 to 55 years.The study of three groups of respondents: physicians, pharmaceutical professionals and consumers on the method of questioning conducted. Respondents were asked about what dosage forms are the most convenient to use; what drugs have the least amount of side effects and about the prospects of developing a new drug from medicinal plants. The study identified the main characteristics that must be met drug thyroid-stimulating actions in oral dosage form, taking into account the origin and presence of side effects depending on the drug substance.The relevance of developing a new Russian herbal drug in the form of oral dosage forms (tablets and capsules) based on the dry extract of Bugleweed European on the basis of All-Russian Institute of Medicinal and Aromatic Plants (VILAR) justified. Therapeutic effect due to the presence in the grass of Bugleweed European and dry extract from this medicinal plant materials o-dihydroxyphenyl: derivatives of caffeic acid and flavonoids, the main component of the sum of-dihydroxyphenyl is rosmarinic acid.
Pages: 45-46
References
- Filatova S.V. Lechenie boleznej shhitovidnoj zhelezy' tradiczionny'mi i netradiczionny'mi sposobami. M.: RIPOL Klassik. 2010. 255 s.
- Nazarova E.A., Tertichnaya Ju.M., Savina A.A.Perspektivy' sozdaniya lekarstvenny'x sredstv na osnove rastitel'nogo sy'r'ya, obladayushhego tireotropny'm dejstviem // Ot rasteniya k preparatu: tradiczii i sovremennost': sb. nauch. trudov Vserossijskoj konferenczii, posvyashhennoj 95-letiyu so dnya rozhdeniya professora A.I. Shretera, M: Shherbinskaya tipografiya. 2014. S. 33-39.
- Ajvazova A.S. Izuchenie tireotropny'x svojstv zyuznika evropejskogo (Lycopus europaeus L.): dissertacziya. 2008. 120 s.
- Sheluxina N.A. Izuchenie metaboloma zyuznika evropejskogo (Lycopus europeus L.) i razrabotka substanczii tireotropnogo dejstviya: Avtoref.?.dis. kand. farm. nauk. M. 2012. 25 s.
- Repina K.N., Babaeva E.Ju., Semkina O.A., Gribkova E.I., Oxotnikova V.F. Izuchenie sy'r'ya zyuznika i razrabotka lekarstvenny'x form na osnovanii marketingovogo analiza antitireoidny'x lekarstvenny'x sredstv // Zhurnal nauchny'x statej «Zdorov'e i obrazovanie v XXI veke». 2012. T.14. №4. S.510.