I.N. Shtan-ko - Junior Research, Laboratory of Organic Materials, Postovsky Institute of Organic Synthesis Ural Brunch of RAS (Ekaterinburg). E-mail: intosova@gmail.com
A.N. Bondarev - Post-graduate Student, Laboratory of Oganic Materials, Postovsky Institute of Organic Synthesis Ural Brunch of RAS (Ekaterinburg). E-mail: alex.ural@mail.ru
T.G. Khonina - Dr.Sc. (Chem.), Leading Research, Laboratory of Organic Materials, Postovsky Institute of Organic Synthesis Ural Brunch of RAS (Ekaterinburg). E-mail: khonina@ios.uran.ru
N.I. Moskalenko - Ph.D (Chem.), Senior Research, Laboratory of Electrochemical Material Science, Institute of High Temperature Electrochemistry Ural Brunch of RAS (Ekaterinburg). E-mail: n.moskalenko@ihte.uran.ru

Recently, the use of biogenic (essential) microelements in a biologically active form is one of the most promising directions in the development of new medicines. We were the first who obtained the silicon-zinc-glycerol hydrogel by the sol-gel method. Due to the presence of essential microelements of silicon and zinc in a biologically active form, the gel has the wound healing, regeneration and antibacterial activity, and can be recommended for standardization in order to introduce it into the medical practice. The technique for determination of silicon and zinc in a new silicon-zinc-containing hydrogel by the gravimetrical method was developed. The basic validation characteristics of the techniques: specificity, analytical region, linearity, accuracy and precision were determined. The obtained results confirm its validity for the quantitative analysis of silicon and zinc. A comparison of metrological characteristics of the proposed gravimetrical method and pharmacopeia method (atomic absorption spectrometry) was carried out. The data obtained indicate the comparability of the results of the quantitative determination of silicon and zinc by different methods.

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