350 rub
Journal №4 for 2013 г.
Article in number:
Activity of lipid peroxidation and state of the antioxidant defense system in patients with type 2 diabetes
Keywords: lipid peroxidation oxidative stress antioxidant enzymes glutathione tioldisulfide exchange
Authors:
N.P. Mikaelian, I.O. Kulaeva, A.E. Gurina, A.A. Terenev, R.E. Saifullin, K.A. Mikaelian
Abstract:
In type 2 diabetes complicated by diabetic neuropathy develops pronounced oxidative stress that is caused by excessive generation of reactive oxygen forms, a violation of the mechanisms of antioxidant system and uncontrolled activation of lipid peroxidation. Oxidative stress in type 2 diabetes is characterized by the blood products of lipid peroxidation and impaired tioldisulfidnogo exchange. Activation of lipid peroxidation and reduced antioxidant capacity of glutathione in red blood cells in type 2 diabetes can lead to stimulation of spontaneous lipolysis and to the emergence of insulin resistance.
Pages: 64-68
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