R.Sh. Khaziev, A.S. Makarova, L.T. Musina

The purpose of this study was to produce a method of extraction from sage leaves with a high output of diterpenic acids and to learn the antimicrobial activity of these extracts. This study was done on sage leaves received from the retail pharmacy. The conditions providing high output of diterpenic acids, both in ethanolic and in aqueous extracts, were chosen. The estimation of antimicrobial activity of the received extract, measured using the culture of Staphylococcus aureus ATTC 6538-P, has shown direct relation between the amount of diterpenic acids in the extract and its antimicrobial activity. It is offered for the preparation of sage leaves infusions with high antibacterial activity to use 1 % solution of sodium hydrocarbonate instead of water.