350 rub
Journal №10 for 2013 г.
Article in number:
Choosing a basis for technology ointments
Keywords: ointments liquid ointments gels auxiliary substances (essence) (basis) and classification
Authors:
N.S. Miheeva - Post-graduent student, All-Russian Institute of Medicinal and Aromatic Plants, Moscow, Russia
V.F. Okhotnikova - Ph.D. (Pharm.), Manager of Pharmaceutical Technology Section, All-Russian Institute of Medicinal and Aromatic Plants, Moscow, Russia. E-mail: vilarnii@mail.ru
T.A. Sokolskay - Dr.Sc. (Pharm.), Professor, All-Russian Institute of Medicinal and Aromatic Plants, Moscow, Russia
Abstract:
The variety of bases used in the pharmaceutical field, requires classification. Classification of bases for ointments are the sources of receipt, the chemical composition in relation to water. Currently there are no objective measures of consistency ointments and their foundations. Consistency is defined as a set of structural and mechanical (rheological) properties of dosage forms. The structural and mechanical properties of dispersed systems substances include rheological properties, their structure, i.e. ductility, elasticity, and strength. Please be aware that replacement based on changing the viscosity of ointments, then changes the absorption of the active substance.
Pages: 26-28
References

  1. Agapova S.K. Razrabotka sostava i texnologii lekarstvenny'x form Loratadina: Diss. - kand. farm. nauk. Moskva. 2011.
  2. Alekseev K.V. Teoreticheskoe i e'ksperimental'noe obosnovanie primeneniya redkosshity'x akrilovy'x polimerov v texnologii myagkix lekarstvenny'x form (mazej i gelej) i biopreparatov: Avtoreferat diss. - d. farm. n. M., 1993. 59 s.
  3. Alekseev K.V. Sovremenny'e tendenczii v sozdanii, issledovanii i primenenii vspomogatel'ny'x veshhestv v farmaczevticheskoj texnologii // Tendenczii razvitiya farmaczii za rubezhom. M.: VNIIMI. 1985. S. 49-57.
  4. Bagirova V.L., Demina N.B., Kulinchenko N.A. Mazi. Sovremenny'j vzglyad na lekarstvennuyu formu // Farmacziya. 2012. № 2. S. 24-28.
  5. Bezuglaya E.P., Fadejkina A.G., Ly'sokoby'lka A.A., Stolper Ju.M., Skakun N.N., GNCLS. Issledovanie vy'svobozhdeniya nekotory'x lekarstvenny'x veshhestv iz razlichny'x osnov dlya mazej i suppozitoriev // Farmakom. 1999. № 1. S. 26-29.
  6. Gosudarstvennaya farmakopeya SSSR. XI izd. Vy'p. 2. M.: Mediczina. S. 145-146.
  7. Oxotnikova V.F., Kachalina T.V., Balakina M.V., Kachalin D.S., Semkina O.A., Otcz N.Ju., Sakanyan K.M. Sovremennoe sostoyanie i perspektivy' razvitiya texnologii tverdy'x lekarstvenny'x form dlya vnutrennego primeneniya s rastitel'ny'mi suximi e'kstraktami // Voprosy' biologicheskoj, mediczinskoj i farmaczevticheskoj ximii. 2012. № 1. S. 139-143.
  8. Promy'shlennaya texnologiya lekarstv / pod red. prof. V.I. Chueshova. Xar'kov. 2002
  9. Tereshkina O.I., Gus'kova T.A. Informacziya o bezopasnosti vspomogatel'ny'x veshhestv, vxodyashhix v lekarstvenny'e preparaty' // Farmacziya. 2007. № 6. S. 6-9.