E.A. Lugovaya, A.L. Maximov

It is known that, environmental factors typical for the area of habitat influence the shifts in metabolism and the levels of macro- and microelements (ME). To study the levels of ME typical for a certain population has become of importance. Pursuing from this our work was aimed at drawing up a «map» of element disorders occurring in Russia-s Northeast residents based on having made a risk assessment table. The risk assessment table on the element disorders observed in the children (10-14 years old) and adults (20-40 years old) residing in Chukotka and Magadan region was made with accounting for our data of Al, Ca, Cd, Co, Cr, Cu, Fe, Hg, I, K, Mg, Mn, Na, P, Pb, Se, Si, and Zn found in the hair samples and based on the frequencies of elevated (excess) or lowered (deficit) ME concentration calculated from the conventionally permissible levels, that conformed to the upper or lower threshold of the element physiological norm. Found that, the common characteristic of the element system demonstrated by the residents of all the studied areas has been a deep deficit in cobalt, magnesium, iron, calcium, and zinc. Excess in manganese and heavy metals (Al, Cd, Hg) is the most typical for the continental areas while for the coastal area it is deficit in phosphorus. Children proved to have higher summarized percentage of the disorders than adults. In Magadan region the differences in microelement status were found in the residents of the coastal area compared to the continental one. The hair samples taken from the continental residents proved to have the elevated iron, manganese, lead, aluminium, cadmium, and potassium. The continental children ME status features more elevated silicon. In Chukotka-s girls no chromium excess was found while in Magadan region 10-13% of the girls had it. Magnesium excess was fount only in children of Chukotka-s continental area (in 20-41 %) while the rest examined subjects demonstrated its deficit. The boys and male adults residing in the continental area of Chukotka have been automatically enrolled in the risk group due to their chromium excess what can recommend carrying regular prophylactic measurements but individual examination and consultation of a bioelementologist for making up a personal «element portrait» cannot be excluded. To conclude from the above, it-s become possible to plan corrective measurements with given subjects, as well as to carry extra deep examinations with cohorts having most commonly occurred disorders in ME profile in order to reveal latent pathologies.

 

1. Vinogradov A.P.Biogeokhimicheskie provincii // Trudy jubilejjnojj sessii, posvjashh. 100-letiju so dnja rozhdenija V.V. Dokuchaeva. M.; L.: Izd-vo AN SSSR. 1949. S. 59.
2. Kovalskijj V.V. Biokhimicheskie puti prisposobljaemosti organizmov k uslovijam geokhimicheskojj sredy / V kn. Biologicheskaja rol mikroehlementov i ikh primenenie v selskom khozjajjstve i medicine. M.: Nauka. 1974. S. 16-28.
3. Vernadskijj V.I.Problemy biogeokhimii // Trudy biogeokhimicheskojj laboratorii. M. 1980. T. 16. S. 9-26.
4. Avcyn A.P., ZHavoronkov A.A., Strochkova L.S. Principy klassifikacii zabolevanijj biogeokhimicheskojj prirody // Arkhiv patologii. 1983. № 9. S. 3-14.
5. Tedder JU.R., Gordienko P.P. Sovremennoe sostojanie problemy jjodnogo deficita v Arkhangelskojj oblasti // EHkologija. 2002. № 2. S. 6-8.
6. Syso A.I.Biogeokhimicheskie predposylki vozniknovenija zabolevanijj naselenija Novosibirskojj oblasti // Tezisy nauch.-prakt. konf. «Sibirskijj standart zhizni: ehkologija pitanija». Novosibirsk. 1998. S. 90-91.
7. Suslikov V.L. Geokhimicheskaja ehkologija boleznejj. V 4 t. M.: Gelios ARV. 1999. 2000. 407 s.
8. Agadzhanjan N.A., Skalnyjj A.V. KHimicheskie ehlementy v srede obitanija i ehkologicheskijj portret cheloveka. Moskva: Izd-vo KMK. 2001. 83 s.
9. Skalnyjj A.V. EHkologo-fiziologicheskoe obosnovanie ehffektivnosti ispolzovanija makro- i mikroehlementov pri narushenijakh gomeostaza u obsleduemykh iz razlichnykh klimato-geografichekikh regionov: Avtoref. dis. - dokt. med. nauk. M. 2000. 43 s.
10. Skalnyjj A.V., Gorbachev A.L., Veldanova M.V. EHlementnyjj status detejj Severo-Vostoka Rossii. Orenburg: RIK GOU OGU. 2004. 189 s.
11. Seljatickaja V.G., Sukhinina S.JU., Poznjakovskijj V.M. i dr. Soderzhanie jjoda v pitevojj vode, pishhevykh produktakh i ego ehkskrecija s mochojj u shkolnikov Novosibirska // Voprosy pitanija. 1996. № 1. S. 27-29.
12. Palchikova N.A., Seljatickaja V.G., Gerasimova I.SH. i dr. JJoddeficitnye sostojanija i podkhody k ikh profilaktike u detejj i podrostkov, prozhivajushhikh v Novosibirske (itogi 10-letnego izuchenija) // Mikroehlementy v medicine. 2001. T. 2. Vyp. 4. S. 23-30.
13. Bulban A.P. Sravnitelnaja ehkologo-fiziologicheskaja kharakteristika mikroehlementnogo statusa naselenija Primorskojj i Kontinentalnojj territorijj Magadanskojj oblasti: Avtoref. dis. - kand. biol. nauk. Magadan: SMU. 2005. 23 s.
14. Gorbachev A.L. EHlementnyjj status naselenija v svjazi s khimicheskim sostavom pitevojj vody // Mikroehlementy v medicine. 2006. № 7 (2). S. 11-24.
15. Korchina T.JA. Korreljacionnye svjazi mezhdu koncentraciejj khimicheskikh ehlementov v volosakh aborigenov Tjumenskogo severa i ikh soderzhaniem v prirodnykh vodakh regiona // Vestnik vosstanovitelnojj mediciny. 2008. № 5A (28). S. 38-41.
16. Gorbachev A.L., Dobrodeeva L.K., Tedder JU.R., SHacova E.N. Biogeokhimicheskaja kharakteristika severnykh regionov. Mikroehlementnyjj status naselenija Arkhangelskojj oblasti i prognoz razvitija ehndemicheskikh zabolevanijj // EHkologija cheloveka. 2007. № 1. S. 4-11.
17. Skalnyjj A.V., JAcyk G.V., Odinaeva N.D. Mikroehlementozy u detejj: rasprostranennost i puti korrekcii. M.: OOO «Galereja-Print». 2002. 86 s.
18. Skalnyjj A.V. Mikroehlementozy cheloveka (diagnostika i lechenie). M.: Nauchnyjj mir. 1999. 96 s.
19. Egorova G.A. EHlementnyjj status vzroslogo naselenija, prozhivajushhego v razlichnykh mediko-geograficheskikh zonakh respubliki Sakha (JAkutija) // EHkologija cheloveka. 2007. № 1. S. 55-59.
20. Gorbachev A.L., Efimova A.V., Bulban A.P., Lugovaja E.A. Osobennosti ehlementnogo statusa zhitelejj razlichnykh prirodno-geograficheskikh territorijj Magadanskogo regiona // EHkologija cheloveka. 2003. № 6. S. 12-16.
21. Gorbachev A.L., Skalnyjj A.V., Lugovaja E.A., Lomakin JU.V. Nekotorye zakonomernosti ehlementnogo statusa zhitelejj severnykh regionov Rossii na fone biogeokhimicheskojj kharakteristiki Severa // Vestnik vosstanovitelnojj mediciny. 2008. № 5A (28). S. 22-25.
22. Lugovaja E.A., Bulban A.P. Mikroehlementnyjj profil detskogo i vzroslogo naselenija Magadanskojj oblasti // Materialy Vseross. konf. «Nauka Severo-Vostoka Rossii - nachalo veka». Magadan: SVNC DVO RAN. 2005. S. 483-485.
23. Lugovaja E.A., Godovykh T.V. Sravnitelnaja kharakteristika ehlementnogo statusa detejj 6-14 let, prozhivajushhikh v g.Magadane i na CHukotke // Materialy II Mezhdunar. nauch. konf. «Problemy ehkologii, bezopasnosti zhiznedejatelnosti i racionalnogo prirodopolzovanija Dalnego Vostoka i stran ATR». Vladivostok: DVGTU. 2006. S. 355-358.
24. Lugovaja E.A., Godovykh T.V. Osobennosti soderzhanija makro- i mikroehlementov v organizme detejj Severo-Vostoka Rossii // Tezisy dokl. KHKH Sezda Fiziologicheskogo obshhestva imeni I.P. Pavlova. M.: Izd. dom «Russkijj vrach». 2007. S. 312-313.
25. Lugovaja E.A., Maksimov A.L. Osobennosti mikroehlementnogo statusa devochek razlichnykh rajjonov Magadanskojj oblasti // EHkologija cheloveka. 2007. № 1. S. 24-29.
26. Lugovaja E.A., Maksimov A.L. Polovozrastnye otlichija ehlementnojj sistemy u detejj i podrostkov Evropejjskogo i Aziatskogo Severa // Zdorove naselenija i sreda obitanija. 2011. № 1 (214). S. 39-42.
27. Lugovaja E.A.Sostojanie makro- i mikroehlementnogo balansa u junoshejj, urozhencev razlichnykh klimatogeograficheskikh zon Magadanskojj oblasti // Materialy III Mezhregion. konf. molodykh uchenykh «Nauchnaja molodezh ? Severo-Vostoku Rossii». Magadan: SVNC DVO RAN. 2010. S. 90-91.
28. Skalnyjj A.V.Ustanovlenie granic dopustimogo soderzhanija khimicheskikh ehlementov v volosakh detejj s primeneniem centilnykh shkal // Vestnik SPb Gos. med. akademii im. I.I. Mechnikova. 2002. № 1-2 (3). S. 62-65.
29. Skalnyjj A.V. Referentnye znachenija koncentracii khimicheskikh ehlementov v volosakh, poluchennye metodom ISP_AEHS (ANO Centr bioticheskojj mediciny) // Mikroehlementy v medicine: 2003. T. 4. Vyp. 1. S. 7-11.
30. Demidov V.A. Sravnitelnaja ehkologo-fiziologicheskaja kharakteristika ehlementnogo gomeostaza zhitelejj razlichnykh rajjonov Moskovskojj oblasti: Avtoref. dis. - kand. biol. nauk. M. 2001. 25 s.
31. Godovykh T.V., Godovykh V.V. Zdorove detejj CHukotki. Magadan: SVNC DVO RAN. 2006. 196 s.
32. Nozdrjukhina L.R.Biologicheskaja rol mikroehlementov v organizme zhivotnykh i cheloveka. M.: Nauka. 1977. 184 s.
33. ZHavoronkov A.A. Mikroehlementozy jatrogennogo proiskhozhdenija // Arkhiv patologii. 1991. T. 53. № 11. S. 73-77.
34. Gorbachev A.L. Strukturno-funkcionalnye osobennosti tireoidnojj sistemy cheloveka i ego mikroehlementnyjj status v uslovijakh Severo-Vostoka Rossii: Avtoref. dis - dokt. biol. nauk. Arkhangelsk. 2002. 42 s.