Yu.I. Denisov-Nickolsky, I.V. Matveychuk, V.V. Rozanov

The article presents modern trends in the science of structural and functional connections of a bone tissue with the use of innovating technologies.The new method of removal of a bone brain from samples of compact and spongy substance of a bone, intended for the purposes of bioimplantology, is submitted. Considered are modern trends in fundamental and applied solutions for biomaterial science, based on the application of new integrated highly informative research methods combined with the traditional ones. The possibilities and prospects of the high technologies adoption in solutions of the problems in experimental morphology and medicine are showed. The authors describe their experience for study of structural and functional connections in the compact and spongy bone tissues after high energy hydro-jet cutting. The different experimental methods such as optical and scanning electron microscopy as well as acoustic microscopy were used for a valuation of the destructive changes of surface relief and structure of compact and spongy bone tissues after high energy hydro-jet cutting. The comparison of acoustic parameters with density and mechanical strength of the compact bone samples in the course of experimental modelling various conditions including composition changes has been performed. It has been established, that sound velocity is in a strong dependance with mineral and/or organic content. The acoustic parameters changes are in a good relation with the mechanical strength indices obtained in mechanical compressive tests. In a serie of various experimental conditions sound velocity proved to be more correct and informative characteristic than density.The questions connected with the study of elementary contents of biological tissues and synthetic materials of medical appliance. The possibilities and the prospects of the appliance of laser mass-spectrometry method for the analysis of materials with different origin (natural, synthetic) are shown as well. The importance of further development and growth of this method with the aim of solution of certain problems within the boundaries of «Reproduction and bioprotheses», as well as clinical microelementhology are remarked.