350 rub
Journal №1 for 2012 г.
Article in number:
The Analysis of Cytostatic And Anticancer Activity of the New Hestogen Buterol by Use of The Cancer Cells Culture As the Test-System
Keywords: cell culture bio-test gestagens cytostatic effect
Authors:
E.V. Odintsova, T.A. Fedotcheva, N.L. Shimanovskii, V.V. Banin
Abstract:
Cytostatic and anticancer effects of new synthetic gestagen Buterol were studed by the using of cell culture MCF-7 as the biotest-system. Buterol has cytostatic action compared with the analogues (progesterone, medroxiprogesterone acetate). This effects are connected with the alteration of the hormone receptors expression, expression of apoptosis regulating proteins (Bcl-2, Bax) and, possible, influence on the cell cycle.
Pages: 93-97
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