G.I. Klimakhin, N.V. Macarova, V.V. Semikin, V.S. Fonin

There were studied in VILAR for 80 years over 200 species of 52 families of medicinal plants, while over 60 plants were cultivated, intensive agrotechnologic cultivation works were carried out. Introduction of research works in specialized economic establishments of «Soyuzlekrasprom» promotes expanding marketable plantations of medicinal plants and multiple extension of production (manufacture) and nomenclature of crude drugs. Annual production of crude drugs of cultivated plants in 1980-1990 was increased in 22 fold comparing with 1940-1950. Crude drugs part of cultivated plants in total volume of its production in 1990 was 42 % comparing 5 % in 1940. There was carried out successful introduction of 3 new medicinal plants in 2001-2011. Oenothera biennis L. (Onagraceae) is the prime source for production of essential polyunsaturated fatty acids. Its seeds contain 20-23 % fatty oil, the basic part of which is linoleic (C 18:2) - 70-78 % and gamma-linolenic (C 18:3) - 8-10% acids. According to the information from some foreign pharmaceutical firms Oenothera oil possesses antioxidant and cardioprotective acion, widely used in medicine and cosmetology. At the pilot plantation of VILAR there were produced over 1 t/ga of seeds, containing 9,1 % of gamma-linolenic acids in oil. Starts from 2008 there was carried out selection work in the institute. Potentilla alba L. is the perennial plant (Rosaceae), natural resources of wtich are limited. The roots possesses regulatory activity on thyroid gland. There were studied peculiarities of its growth and developments at the Moscow region. There was worked out the intensive method of its reproduction, the basic elements of agrotechnology ware determined, providing the yield of 3,5-4,5 t/ga of the quality crude drugs. Serratula coronata L. is the perennial glass of Asteaceae, which is prospective producent of phytoekdisteroids, possessing biostimulatory action for human and animals. 20-hydroxyekdizone (20E) was recommended to use in combination with the drugs of adaptogenic, cardiotropic, antiulcer and anabolic action. There was shown wide prospects of its cultivation in the central part of non-blac soil area. There was worked out agricultural technology for production 6-8 t/ga of dry grass containing 0,8-1,2 % 20E at the phase of buds from 3-8 annual plantations. There were revealed 3 best population. Positive results of medicinal plants introduction in Russia have allowed good prospects for working out and production of original phytodrugs, cosmetic material and food additives, provided by domestic raw materials base.